Agonists alpha-adrenergic: whakaahuatanga, tono, parau tumu

Agonists Ko te rōpū o taero, te hua o nei e pā ana te ki whakaongaonga o receptors adrenergic kei roto i te whekau, me taiepa iaia. Kua wehea adrenoceptors katoa ki te maha ngā rōpū i runga i te localization takawaenga pānga me te kaha ki te hanga i complexes ki te matū kaha rānei. Alpha-agonists whakaongaonga pānga i runga i receptors alpha-adrenergic, meinga he whakautu motuhake o te tinana.

He aha te mea he receptors Arepa-adrenergic

A1-adrenoceptors kei i runga i te kiriuhi mata o ngā pūtau i roto i te synapse whakautu ki norepinephrine, tukua nei e mutunga karere o nga neurons postganglionic o te pūnaha io pukuaroha. Paetata i roto i nga pera o ërä iti. receptor whakaongaonga ai vasospasm, takawhita, heke uruhanga o te taiepa matua, te whakaiti i te mau faaiteraa o tauhohe inflammatory i roto i te tinana.

He receptors 2-adrenergic kei waho te synapses i runga i te membrane pūtau presynaptic. Tauhohe ki te mahi o te noradrenaline me Adrenaline. receptor whakaongaonga ai te pepepe me, whakakitea nei e hypotension me te whakangā iaia.

mōhiohio General e pā ana ki adrenomimetikami

Arepa me beta-agonists, e e takitahi e pā ana ki te tūtohutanga ki a ratou receptors ka meinga te pānga o te Adrenaline ranei mana noradrenaline, ka karanga nga tikanga o te mahi tika.

Ko te hua o te mana o te raau taero e puta me te pānga autaki e faaite ake e whakaongaonga whakatupuranga ake neurotransmitters, ārai ratou kinonga, faarahi i te kukū o hopearaa karere.

E whakaritea Adrenoceptor agonists ki te tikanga e whai ake nei:

• kore ngakau, hypotension nui, tiango, ru, hopu cardiac;
• huangō, bronchospasm;
• pēhanga intraocular teitei;
• mate inflammatory o te membrane mucous o nga kanohi, me te ihu;
• pōroa, hypoglycemic;
• rehunga rohe.

agonists alpha-adrenergic

taero rōpū kau whiriwhiri (mahi i runga i tetahi momo o receptor) me kore-whiriwhiri (A1 excitation me A2-receptors) te tikanga. Non-whiriwhiri Arepa-agonists tuku tika noradrenaline, whakaongaonga me te mahi i runga i te beta-receptors.

Alpha-agonists e pā A1-receptors - drugs antishock whakamahia ki te hekenga koi i roto i te pēhanga toto. Ka taea te whakamahi i te reira topically, meinga constriction o nga arterioles e papahewa whai hua ranei i roto i te Rhinitis mate pāwera. Rōpū taero mohiotia:

• "Midodrin";
• "Mezaton";
• "Etilefrin".

agonists alpha-adrenergic, e pa ana te receptor A2, mohiotia atu ki te papatipu whānui o te taupori no o tona tono ao. māngai Top - "Xylometazoline," "te whārangi", "Sanorin", "Visine". Whakamahia i roto i te therapy o mate inflammatory o te kanohi, me te ihu (pīkaru, Rhinitis, pakohu kakā).

E mohiotia ana te raau taero mo ratou pānga vasoconstrictor, e faaore popoketanga nasal. kia tango i te whakamahi o moni wahi anake i raro i te mātakitaki o te mātanga, rite te roa fariiraa whakakeke kia meinga te whanaketanga o te pūmautanga tarukino me te mucosal atrophy.

whakarite ano Young tamariki māngai kei roto agonists alpha-adrenergic. Drugs i roto i tenei take i te kukū o raro o te taonga kaha. whakamahia ana te taua ahua kei roto i te maimoatanga o tangata e mate ana i te mate huka, me te āmai.

agonists alpha-adrenergic, excitatory A2-receptors, a ngā āpiha pū whakakapi ( "methyldopa", "Clonidine", "Katapresan"). Ratou pānga ko e whai ake:

• pānga hypotensive;
• heke auau ngakau;
• mārie;
• manawa mamae iti;
• heke secretion o lacrimal me salivary repe;
• heke secretion o te wai i roto i te whēkau iti.

"Mezaton"

hāngai faaineineraa i runga i phenylephrine hydrochloride, meinga pēhanga toto nui haere. titau Ko tōna tono dosing tika rite taea auau ngakau heke pūpū. "Mezaton" faarahi te pēhanga ata i roto i te rite ki ētahi atu taero, engari ko atu roa te pānga.

Tuhinga tikanga:

• hypotension, tiango;
• faaineineraa no te pokanga;
• vasomotor Rhinitis ;
• rehunga rohe;
• poisoning o ngā etiologies.

Ko te hiahia hoki ngā hua tonu rapua e whakahaere rō-uaua. Kei te patia te raau ano ki te uaua, subcutaneously, intranasally.

"Xylometazoline"

Ko te raau ia te taua ingoa te taonga kaha, he wahi o "galazolin" "Otrivin" "ksimelin" "Dlyanosa". Kei te whakamahia te reira i roto i te maimoatanga wā o te Rhinitis whakapeka hopuhopu, pakohu kakā, he tarutaru kirika, pāpāho otitis, i roto i te faaineineraa no te nga ngā tukanga whakahaere tātaritanga ranei o te kōhao nasal.

Kei te whakaputaina te reira i roto i te puka o te rehu, pata, me tono nasal rā. Rehu whakaaetia mō ngā tamariki i te 12 tau o te tau. Kia tūpato i whakaritea i roto i te tikanga e whai ake nei:

• angina;
• hohipera;
• mate thyroid;
• prostatic hyperplasia;
• mate huka;
• hapūtanga.

"Clonidine"

Ko te tarukino Ko te agonists alpha-adrenoceptor. hāngai ana te tikanga o te mahi "clonidine" kei runga i te excitation o receptors A2-adrenergic, hua i roto i te hekenga i roto i te pēhanga, te whanaketanga o te whakarehu iti me te whakarokiroki.

Whānui e whakamahia ana i roto i ngā ngā o takawhita, raruraru hypertensive, ki atawhai whakaeke papahewa i roto i ngā ki ētahi atu taero mo te maimoatanga o te tarukino me te waipiro ma'unimā.

"Clonidine" contraindicated te wā hapū, engari i roto i te take o te gestosis nui i roto i te wāhanga i muri mai, ka te painga ki te whaea e tami te mōrea o te kino ki te kukune, e taea ki te whakamahi i pota iti o te tarukino i roto i ngā ki ētahi atu taero.

"Visine"

Vasoconstrictor tarukino i roto i tetryzoline whakamahia i roto i te Ophthalmology. I raro i puta tona mana mydriasis, whakaiti edema conjunctival, iti i roto i te hanga o te inu intraocular. Kei te whakamahia te reira i roto i te maimoatanga o te pīkaru mate pāwera, i aunoa, tinana matū ranei mahi o āpiha ke i runga i te kamo mucous.

agonists Arepa tuwhena rawa

whakakitea tuwhena rawa te huringa tamau characterizing te pānga o te Arepa-agonists. Te manawanui āwangawanga pēhanga toto tiketike, nui haere disorders manawataki auau ngakau. I roto i tenei wā ko reira taea te whanaketanga o te patu edema pūkahukahu ranei.

Therapy overdosing ko ki te tono i te rōpū e whai ake nei o taero:

1. sympatholytic piringa whakapōrearea i te tuku o ponana karere i roto i te taha, me te i roto i te pūnaha io. auau ngakau te kupu, heke te pēhanga heke te me ātete piringa.
2. te raveraa ra konupūmā hāngai ana ārai i te rere o katote konupūmā ki te pūtau. uaua cardiac whakaiti hāora tono, heke contractility whakapiki i reira whakangā i roto i diastole, whakawhānui rōpū pera katoa.
3. whakatairanga taero Myotropic whakangā o uaua maeneene, tae atu uaua, me te taiepa iaia.

agonists alpha-adrenergic, te whakamahi o nei he rōpū nui o pānuitanga, e rapu kōwhiringa tupato o inenga, te aroturuki i te hiko-, te pēhanga toto, te toto piringa.