Benzylpenicillin konutai tote: tohutohu mō te whakamahi. ture tono

I roto i tēnei tuhinga ka kōrero tatou e pā ana ki taua faaineineraa rite "konutai tote Benzylpenicillin". Ka hipokina tohutohu mō te whakamahi, tohu, inenga me ngā tūtohutanga mō te whakamahi i roto i te tuhinga. I tua atu, whakaaro tatou nga āhuatanga pharmacological o te raau taero, ngā pānga taha taea me taunekeneke tarukino ki ētahi atu rongoa.

tapeke

Ko te tarukino ko te kaihoko antimicrobial me te rongoā paturopi no ki te rōpū rongoā paturopi. Benzylpenicillin konutai tote ano, tohutohu hoki te whakamahi o nei e kia te aroaro raro e whakaputaina e ngā harore.

Drugs i roto i tenei rōpū te whakamahia mō te whakahaere intramuscular, pānga i runga i ngā kopa me whēkau i roto i nei te toto homai e te nui iti o te rongoā paturopi. Ki timata te tarukino ki te whai pānga i runga i te roro, me te filosilivá aho, me meninges, whakahaere subarachnoid.

Benzylpenicillin konutai tote, tohutohu mō te whakamahi: mahi pharmacologically

He whai hua ki huakita karamu-pai, e ngā te tarukino:

• staphylococci;
• streptococci;
• pneumococci;
• diphtheria ;
• Anthrax coli;
• takohe (ora i roto i te ngaro o te hāora) sporulating tokotoko.

I tua atu, he kaha ki Gram cocci tōraro (meningococcus, gonococcus), spirochetes, actinomycetes me ētahi atu microorganisms te tarukino. he hua ki huaketo, rickettsiae, harore, hātare rongoā paturopi konutai tote.

Tarukino taumahatanga ātete o staphylococci, e he ahei o te whakaputa te penicillinase paru, vavahiraa i benzylpenicillin. Ko te medicament whakaaturia mahi iti i roto i te maimoatanga o Pseudomonas aeruginosa, huakita intestinal me ētahi atu microorganisms, e e taea ki te tohatoha rerekē moni o penicillinase.

Pharmacokinetics

I roto i te tarukino intramuscular tere tomo te bloodstream, i te wahi e tukua ki te fluids tinana me te kopa. Ki te whakaaro ki te inu cerebrospinal, ô i reira ki te nui iti o te rongoā paturopi. Te kukū rawa i roto i te toto i muri i tona whakahaere kitea intramuscularly i muri i 30-50 min. Ki te i whakahaere te raau subcutaneously, heke te auau o te absorption te a ka te tau mōrahi o ngā matū i roto i te toto e kitea i roto i te haora.

E toru haora i muri i te werohanga (subcutaneous intramuscular ranei) o benzylpenicillin tohu anake noho i roto i te toto. Na reira, ki te mau tonu i te kukū nui o tarukino i roto i te tinana mo te wa roa, he mea e tika ana ki te wero i roto i nga haora e wha.

A, no te whakahaere pâmuhia, tona kukū o te tarukino tere taka. A, i te tango waha benzylpenicillin ngaro e penicillinase (paru) me wai pekitīlia.

raau excreted excreted i roto i te mimi.

iteraa papû

kia āta kia ako ratou i te aroaro o te whakarite o te tarukino rite rongoā paturopi konutai tote, tohutohu mo te whakamahi, inenga me tohu mo te whakamahi. Kia tīmata a ki te muri. Ko te kupu, whakaritea te te tarukino:

• i roto i mate o nga pūkahukahu, me te wahi romahā;
• nui mate ero;
• endocarditis kitakita;
• sepsis;
• mate me patunga i pangia o te kopa ngohengohe, kiri me kiriuhi mucous;
• weranga;
• mumura o te ua, me te roro, hiako mazgovyh;
• purulent kiripūkahu;
• peritonitis;
• cystitis;
• Pius me te septicaemia;
• te tapû-;
• diphtheria;
• ngangana kirika;
• gonorrhea;
• erysipelas;
• Mate i roto i te whanau hou;
• Anthrax;
• pakewakewa;
• actinomycosis;
• ngā inflammations gynecological;
• mate inflammatory o te korokoro, taringa, me te ihu.

Ngā Ture Whakamahi me te inenga

Tei runga i te momo o te tātaritanga therapy whakamahi benzylpenicillin konutai tote o te tarukino kia whakahaere ai. Ka tohutohu mō te whakamahi, ara o te whakahaere, me te taea inenga kia whakaaro e tatou i roto i tenei wāhanga.

Ko te akoranga o te maimoatanga tarukino e taea muri, i runga i te mate rānei, i te 4 wiki ki te 2 marama atu ara ranei. Ka taea te whakahaere i te raau i roto i te ara e whai ake nei:

• Intramuscularly i roto i te hautahi waho o runga o te gluteal. diluted te faaineineraa e te aroaro whakahaere i roto i maturuturu wai, novocaine konutai ranei otinga pūhaumāota.
• Rō-uaua - .. under anake taua mate kino, pērā i meningitis, endocarditis kitakita, te septicaemia, etc. whakahaere te tarukino te katoa 4 haora te maturuturunga tonu ranei - 30 pata ia meneti mō te 6-12 haora.
• kia hoki kia whakahaerea te reira i endolyumbalno benzylpenicillin konutai tote. Tohutohu mō te whakamahi (tono tikanga) whakarato he tikanga mo te mumura o te roro, me te ua, tae atu i te meninges. patia i te raau e te tino āta - 1-2 meneti.
• He take i reira benzylpenicillin whakamahia mō te injecting te aronga inflammatory. Hei tauira, ka actinomycosis, leishmaniasis kiri, pyoderma ma'i me ētahi atu mate kiri hopuhopu.
• Ki te inhalations - mo te maimoatanga me te ārai o mate o nga pūkahukahu me Airways. Hoki tenei whakaaro, i konatunatua ki te benzylpenicillin otinga konutai pūhaumāota wai māturu ranei. Inhalations kore ake atu i te 2 ngā wā ia ra. Tonu tetahi maimoatanga - i te 10 ki te 30 meneti.
• Kei te patia ano te reira i ki te kōhao pleural peritoneal ranei i roto i te purulent peritonitis kiripūkahu ranei.
• I roto i te puka o hake, hinu, ranu hou, hinu me puehu - mo weranga, patunga o te kiko ngawari, me te tapû-al.
• Ano, whakamahia te otinga tarukino mo te maimoatanga o runga mate romahā me te i roto i te Ophthalmology.

Ka taea te whakamahi rongoā paturopi i roto i therapy tahi ki ētahi atu paturopi me taka sulfanilamide. Ai e whakaū i te tikanga te pānga haumanu o raau taero whakamahia.

pānga taha

Ka taea hoki te whai te reira i te pānga kino o te benzylpenicillin konutai. Tohutohu mō te whakamahi tuhipoka e whakaaturia e ratou i te whakahaere rō-uaua o te tarukino tino maha.

Fele, e pā ana te pānga taha ki tauhohe mate pāwera ki te tarukino. I roto i te tohu kino kitea:

• candidiasis;
• pununga honé;
• kirika;
• pāhoahoa;
• Chills;
• mamae tahi;
• Angioedema;
• eosinophilia;
• momo ngā o dermatitis;
• kirika;
• lymphadenopathy;
• ru anaphylactic - i roto i te wā tino onge.

contraindications

Ka taea e kore tūroro katoa whakatata therapy ki te medicament o benzylpenicillin konutai tote. Tohutohu mō te whakamahi me te ture o te whakahaere whakarato he maha o contraindications. I roto ia ratou:

• mate pāwera pērā i urticaria, he tarutaru kirika, huangō arahau, aha noa.;
• hypersensitivity ki pärönaki rongoā paturopi;
• whakautu rerekē ki taero;
• mate tukumate ātete ki te horopeta wae o benzylpenicillin.

Ko te kupu whakataki o te endolyumbarnym tarukino rāhuitia taea i roto i te haurangi.

Pregnancy me te hohipera

Whakaritea i roto i te hapū anake, ki te he nui atu i te tūpono ki a ia tamaiti e parauhia te painga ki te maimoatanga o te wahine. Te kore, e kore e faaterehia te tarukino. whakaritea ōwehenga mōrea me te kakama e te rata haere.

Ki te tika, kia mutu te whakahaere o te tarukino i roto i te hohipera ū.

āhuatanga

Drug taonga benzylpenicillin konutai tote e te puka o ma paura, tioata pai ki te reka kawa i te mea ohie wairewa i roto i te wai.

Kei te ngāwari te raau huna e waikawa, kawakore, māngai oxidizing, whākōkī penicillinase, me te whakawera. Whakapaia taonga tarukino me kia tonu i mua ki te whakahaere.

mehua whakatūpato

whakahaere te raau e anake i roto i te hōhipera i te whakahaunga o te tākuta, me te i raro i tona mātakitaki. Ki te wahi o te therapy kia mahara e te benzylpenicillin horopeta iti ranei whakamutunga wawe o te maimoatanga e taea arahi ki te hanganga o taumahatanga ātete o microorganisms. I roto i te kaupapa o te ātete ki te maimoatanga tarukino tonu te tahi atu paturopi.

Ko te huru ki tauhohe mate pāwera whakahaere tahi me tarukino antihistaminic ko benzylpenicillin konutai. Tohutohu mō te whakamahi (mahi o te tarukino i roto i tona taipitopito ngā whakaritea) ngā e ka tonu mutu te faaiteraa mate pāwera therapy manawanui.

I roto i etahi rōpū o tūroro (ruhiruhia, kohungahunga, ngoikore e mate) kia whai resistance ki benzylpenicillin, e ai te whanaketanga o te superinfection.

Ki te whakamahi auroa, e taea te tāmia te rongoā paturopi wahi ngaro e microflora intestinal, ārahi ki te hanga iti o huaora o rōpū B. reira prophylactically ki tūroro maha whakaritea huaora B1, B12, me ētahi atu ranei.

Ki te, i muri i te tīmatanga o te therapy mō te 3 ra kihai i kite i tetahi pānga, he mea e tika ana ki te haere ki te maimoatanga ngā ranei tautapa i te rongoā paturopi hou.

Ara

Whakatūpatotanga whakaritea iwi ki te kore te ngakau, me te mahi tākihi waimaero benzylpenicillin konutai tote. Tohutohu mō te whakamahi taunaki hoki e kia hoatu tokanga makehe ki te hunga tūroro e kua kite hypersensitivity ki cephalosporins.

tūtohutia No te mea o te pea o te superinfection fungal te ki whakahau āpiha anti-fungal.

Ngā pāhekoheko ki ētahi atu taero

I roto i te whakarite o aua paturopi, e whai bacteriostatic, mahi bactericidal o rongoā paturopi iti.

Te faaineineraa "Probenecid" kua he taonga ki te whakaiti i secretion tubular o te rongoā paturopi e hua i roto i te hua i roto i te taumata toto o te muri, me te, rite te putanga, whakanui i te wa tango i te reira i te tinana.