Ngā pūtau Sertoli (sustentotsit): mahi

Ko te mana te kawenga mō te uri i roto i nga tangata, ka karanga nga testes. E whakaputaina ratou pūtau sex - parāoa me hormones, pērā i te testosterone. Ko te kikokiko, me te histological hanganga o testes i matatini tane, rite enei tinana kawe i te maha ngā mahi. kawea ratou spermatogenesis - te hanganga, me te whanaketanga o ngā pūtau iroriki. te mahi hoki komurumurua endocrine mahi. E tū ana i roto i te waihakihaki putea motuhake - raho. He te tonu te pāmahana motuhake, i te mea paku raro atu i roto i te tahi atu wahi o te tinana.

Testes i āhua porotītaha, he pā ana ki 4 cm te roa, me te 3 whanui ratou rahi. Tikanga, i reira kia kia he karawhiti iti i roto i te gonads. wehea ia anga hua e pātaki ki te plurality o poro. Kei roto ratou i te awa seminiferous ore hanga plexus testicular. Ko tōna aerodynamics efferent tomo nga pōkai raho. He te hanga e te nuinga o te parāoa - matenga. I muri mai - e ngā takere i roto i te tātea vas, kua tonoa nei ki te tōngāmimi. I tua atu, te whakawhānui i ratou, ka tomo ki te tahi atu okana o te pūnaha whakaputa uri toa - te repeure. I mua tenei, i hanga te hongere e i roto i te tau mahani ejaculatory, e kua he putanga i roto i te rohe o te taiawa mimi.

hanganga Histological o te komurumurua i roto i nga tangata

Toa gonads ngā o aho tātea, me te kiko interstitial. I waho o ratou albuginea pukupuku. Kei te māngai ia e kiko tūhonohono mātotoru. kanawa Albuginea ki te tinana. Taha o reira thickens ki te hanga i te raho mediastinum. I tenei wāhi, e tahuri iho te kiko tūhonohono ki te plurality o whenu. hanga ana e ratou nga lobules roto i he tubules ore. E māngai ratou e te wae hanganga e whai ake nei:

1. pūtau Sertoli - sustentotsit. Fakataha ki te atu āhuatanga whai wāhi i roto i te hanganga o te toto-raho arai.
2. Pūtau, i roto i nei kawea te spermatogenesis.
3. Myofibroblasts. Ratou ingoa atu - pūtau peritubular. Ko te mahi matua o te myofibroblast - ko ki te whakarite i te whakatairanga o te inu huero o awa crimped.

I tua atu, i te hanganga o te hua manu he kiko interstitial. Ko reira e pā ana ki te 15%. kanohi kiko interstitial e āhuatanga pērā i ngā pūtau Leydig, macrophages, tōiti, me te pera i runga i. D. Ki te he kawenga mō te hanganga o ngā pūtau sex nga awa ore, i reira ko te hanganga me te hanga o hormones tane.

pūtau Sertoli: hanganga

pūtau Sertoli i te āhua elongated. Ratou rahi Ko e pā ana ki 20-40 microns. Ko te wae hanganga tika nui e te hunga e karangatia e tautoko pūtau rerekē tenei. I roto i te cytoplasm o enei pūtau kei maha organelles. I roto ia ratou:

1. Matua. He he kōhikohiko, ētahi wā te reira - āhua pea-. tohaina te pūpūira i roto i te karihi te kāore.
2. EPS Smooth me taratara. Ko te tuatahi - he kawenga mo te hanga o hormones pūtaiaki, te tuarua - whakarato kōtuitanga pūmua.
3. taputapu Golgi. Ngā mihi ki tenei organelle, i reira te mea he kōtuitanga whakamutunga, rokiroki, me te tango o ngā hua.
4. Lysosomes - he wāhi i roto i te phagocytosis.
5. Microfilaments. E whai wāhi ēnei organelles i te matuatanga o te parāoa.

I tua atu, kei ia pūtau whakauru Sertoli ngako. Kei Sustentotsitov turanga kei i runga i te taiepa o nga tubules seminiferous, me te matamata - mata i roto i to ratou lumen.

pūtau Sertoli: mahi

pūtau Sertoli Ko tetahi o nga wae hanga nga tubules seminiferous ore. Ko reira o faufaa nui, pera whai wāhi i roto i te tukanga o te spermatogenesis, me te kōtuitui o hormones tane. He te mahi e whai ake nei o ngā pūtau Sertoli:

1. Arataukai. Ēnei āhuatanga whakarato ngā pūtau parāoa teeki ki te hāora, me ngā matūkai.
2. Paruru. kua he lysosomes cytoplasm ia pūtau - organelles whai wāhi i roto i te phagocytosis. mimiti ratou, ka hangarua nga hua whāwehe, mo te tauira, whatiwhatinga o spermatids mate.
3. Whakarato toto-raho arai. whakarite ana tēnei mahi e tata whakapā pūtau-pūtau. hiahiatia ana te arai kei te ki wehe i te pūtau tane i te toto, me te matū i roto i roto i reira. I tua atu, ārai reira te kătahi o antigens parāoa i roto i te wē. te whakaiti i tenei te mōrea o te whakawhanake i mumura autoimmune.
4. mahi endocrine. E whai wāhi ngā pūtau Sertoli i te hanganga o hormones sex.

Sustentotsity tika mo te hanganga me te tiaki o te taiao motuhake i roto i nei parāoa whakawhanake pai. Kei te mohiotia te reira e ko rerekē i te wē toto te hanganga katote o ngā pūtau Sertoli. Ko raro konutai kukū, me te ihirangi pāhare pāporo, i runga i te anga ke, nui haere. I tua atu, i roto i Sertoli pūtau synthesize maha matū kaha biologically. I roto ia ratou - te prostaglandins, cytokines, follistatin, āhuatanga tipu me te wehenga, opioids, etc ...

Taumahi me te hanganga o ngā pūtau Leydig

Leydig pūtau he wahi kiko interstitial testicular. Ratou rahi Ko e pā ana ki 20 microns. Ko te gonads tane he neke atu i te 200 * 10 ⁶ ngā pūtau Leydig. Ko te hanganga o enei āhuatanga āhuatanga ko te karihi, me te foamy cytoplasm nui porotītaha. He vacuoles kei roto pūmua lipofuscin. Kei te hanga e te reira e te pirau o te ngako i roto i te kau o te kōtuitui o hormones pūtaiaki. I tua atu, i roto i te cytoplasm e 1 2 ranei nucleolus kei roto RNA me te pūmua. Ko te mahi matua o te pūtau Leydig - he testosterone. I tua atu, kei te whai wāhi ratou i roto i te kōtuitui o activin. Tenei taonga whakaongaonga te hanga o FSH i te roro.

He aha te mea te Sertoli pūtau syndrome?

Ko tētahi o nga mate onge o te pūnaha whakaputa uri toa ko te syndrome pūtau Sertoli. whakaaro te faaiteraa matua o tenei mate e ki te pākoko. pā ana te mate te ki kōhikohiko congenital, mai i te kitea i te reira aplasia (he whakaiti nui ngaro ranei) o kiko testicular embryonic. Ka rite ki te hua o te pakaru o tubules seminiferous tenei whakawhanake. Ko te anake huānga e kore te i pakaru - ko te pūtau Sertoli. Ko tētahi atu ingoa mō tenei mate - he syndrome del Castillo. Wāhanga o ngā pūtau Sertoli te whakamamaetia tonu e hōloa, Heoi, te nuinga o ratou - he noa. Ahakoa tenei, i te epithelium o nga tubules atrophied. kahore e Spermatozoa i roto i tenei māuiuitanga i hanga.

Waimaero o te mahi o ngā pūtau Leydig

Ki te raru te kino Leydig pūtau ratou mahi tuatahi - kōtuitanga testosterone. Ka rite ki te hua, tohu pērā i:

1. papatipu uaua iti.
2. Ngaro o ngā āhuatanga tuarua sex (tupu o makawe o momo tane tinana, reo).
3. Tūkinotanga o libido.
4. kiato wheua heke.