"Oseltamivir": tohutohu mō te whakamahi, analogs, he whakaahuatanga o te tarukino

He aha whakahau te tarukino "Oseltamivir"? ka whakaahuatia te iti atu tohutohu mō te whakamahi, analogs, tohu me contraindications o te tarukino. korero matou hoki koutou e pā ana ki te puka i roto i nei ka taea e koe te hoko mea medicament, he aha ngā āhuatanga kua reira, ahakoa te pānga taha, me te pera i runga i. d.

Te āhua, te hanga, te whakaahuatanga o te tarukino

I roto i te hoko o te raau taero mai roto i te puka o capsules kōwhai-ma. "Oseltamivir" - ko te prodrug. A, no te ingested, kua hydrolyzed reira, ka tahuri ki te whakauru hohe - carboxylate oseltamivir.

I tua atu ki te capsules me te medicament tukua te i roto i te puka o te paura marama mō te whakatārewatanga-waha.

āhuatanga rongoā

tarukino "Oseltamivir" pehea e mahi i te reira? Tohutohu i runga i te tono kī e hāngai ana te pānga haumanu o tenei rongoā i runga i pehanga o mahi o whākōkī, e kua kei i runga i te mata o te huaketo virion rewharewha.

Ki runga ki te taenga o te medicament ki te tinana tangata puta tona wāhanga matua te ki te metabolite hohe. Ko te kupu, oseltamivir carboxylate tīpakongia inhibits neuraminidase. Ka rite ki te hua o taua te rongo mutu viral tukanga whakareatanga pūtau.

E ai ki te toi, tango tenei rongoā kia whakahaerea i roto i te 35 haora i muri i te tohu tuatahi o te rewharewha. Anake i roto i tenei ara e taea te heke te roanga o te mate i te 30%, me te tūponotanga o pōauautanga me te pakeke o te tohu - 40%.

Pharmacokinetics o te tarukino

Ahakoa whenumi rongoā te "Oseltamivir"? Tohutohu mō te whakamahi tohu e pā ana ki 90% o te oseltamivir Phosphate i horomia i te wahi Gastro-intestinal. Kei te tahuri te taonga kaha ki te carboxylate o oseltamivir, a ka tomo te tohanga nahanaha.

Mō 3% o te whakauru kaha herea te ki pūmua wē. Ko tōna bioavailability Ko āhua 76-85% me te whakakorenga hawhe-ora - 120 meneti.

Mai i carboxylate oseltamivir tangata ahu e te whatukuhu (tata ki 80%) me te gut (20%). Hawhe-ora o te tarukino ko 6-10 haora.

Tuhinga

He aha whakahau te tarukino "Oseltamivir" (rōpū pāmu -. Māngai huaketo)? E ai ki nga tohutohu, whakamahia te medicament te ki te hamani rewharewha A me B. ano, Kei te maha whakamahia reira mo te ārai o mate viral.

contraindications

E contra "Oseltamivir" (Kua whakaahuatanga o te faaineineraa kua aroaro i runga)? E ai ki nga tohutohu, rāhuitia te tangohanga tarukino te i:

• Hypersensitivity ki te whakauru kaha;
• tākihi kore (e kore, kua haumaru me te aonga o te tarukino i roto i enei tūroro kua tāutuhia);
• i roto i ngā tamariki teina atu i te 1 tau (i reira he papû ore rite ki te hanganga o te BBB i ngā tamariki);
• hapūtanga me te whāngai ū (kore te mohiotia ai ranei excreted te tarukino e i roto i te waiu o nga wahine uma, a ahakoa pānga ki te kukune).

Me mahara hoki käore te reira e kore e tūtohu tenei rongoā mō ngā tamariki i raro i 13 tau, kia rite ki kahore i tohunga i whakaritea haumaru me te aonga o 'Oseltamivir' mo te ārai me te maimoatanga o te rewharewha.

Drug "Oseltamivir": tohutohu mō te whakamahi

Vidal (Medicines Handbook) kei roto ngā mōhiohio whānui i runga i te āhua o me i roto i te aha te inenga kia tangohia e koe te tarukino i roto i te pātai. Heoi, kia tuhia te reira e whakahau te raau kia tākuta anake. I muri i te katoa, ka taea ki te whiriwhiri i te talena maimoatanga tika, e hohoro a whai hua faaore i te tohu kino katoa o te mate viral he mātanga mātanga anake.

Na i roto i te mea inenga whakaritea te "Oseltamivir"? Tohutohu mō te whakamahi tohu e kia whakamahia tenei tarukino i roto i te 2 nga ra i muri i te tīmatanga o te tohu tuatahi o te rewharewha.

Tamariki pakeke atu i 13 tau me ngā pakeke ki te tarukino faaterehia i roto i te nui o 75 mg rua he ra mo te 5 ra. E tika ana kia tonu tuhia e te whakanui ake i te inenga o te tarukino (hei tauira, ki runga ki te 150 mg ia ra) kihai i arahi ki te pānga haumanu nui haere.

Ki te te tarukino e hiahia ana koe ki te tautapa ki ngā tamariki 1-12 nga tau te pakeke, whakaritea te inenga i runga o te tamaiti taimaha tinana rānei.

Kia kore ai rewharewha ki ngā pakeke me ngā tamariki i runga i 13 tau i whakaritea 75 mg 1 kotahi hoki 6 wiki i roto i te ra (hei tauira, i roto i te urutā).

Tūroro ki Cl creatinine iti iho i te 30 ml ia meneti hiahiatia ako inenga (75 mg kotahi hoki 5 ra ia ra).

pānga te taha o te raau taero i muri i ingestion

Tetahi tauhohe kino puta i muri i whakahaere o te faaineineraa 'Oseltamivir'? Tohutohu i runga i te tono ta e te tauhohe kino tino nuitia whakakitea ko te whakapairuaki me te ruaki. I roto i te nuinga o te wā, he ngawari ranei tika whakahuatia enei pānga, me te nuinga o te wā puta i roto i nga ra tuatahi o te maimoatanga.

Me mahara hoki käore te reira e i roto i te tahi mau tūroro, i roto i ngā tūroro i te fariiraa i te raau taero i raro i te arotake, te whakawhanake Bronchitis, te taninito, ohoroa, angina iu, colitis pseudomembranous, anemia, kakā, peke whati, whēwhē peritonsillar me te kirika.

Tino onge i roto i te iwi tango i te tarukino "Oseltamivir", i reira he mamae puku, rongo pouri, nosebleeds me pīkaru. I roto i te nuinga o te wā, enei tauhohe puta kotahi anake, ka ngaro i runga i to ratou ake, ahakoa therapy tonu. e kore e taua ari rapu korenga atu o rongoā.

I muri i te whakarite o te tarukino huaketo i roto i ngā tamariki me ngā taiohi hoki pānga kino whakakitea. Enei ngā pēnei mea rite hikaka, paitini necrolysis epidermal, pupuhi o te arero ranei mata, arrhythmia, whakama, haurangi, me te ähua o te rere huka.

taunekeneke tarukino

Information whiwhi i roto i te akoranga o te akoranga pharmacokinetic me pharmacological kī e whai i te whanaketanga o ngā taunekeneke tarukino hauora tino he pea tenei tarukino.

Ko te tohutohu ngā ki te tarukino, kua mea i te reira e te tono tukutahi o te medicament ki probenecid arata'i ki te hua i roto i AUC o te metabolite kaha o 2 nga wa. Heoi, e kore te horopeta whakatikatikanga e hiahiatia ana.

take o te tuwhena rawa

He aha e te tohu i kite i roto i te tūroro ki "Oseltamivir" pota teitei o te tarukino? Reviews me tohutohu kī e ki te rā whakatika kahore take pērā. Heoi, toketaá kotahi o rongoā patu huaketo e taea meinga ruaki whakapairuaki ranei.

Hei whakatau i enei tohu, therapy symptomatic.

tūtohutanga motuhake mō te fariiraa i rongoā

He aha e hiahia ana koe ki te mohio i te manawanui, i mua i te tango "Oseltamivir"? (Kia wheako mō ngā tamariki, me ngā pakeke rerekē ngā pānga taha) Tohutohu mō te whakamahi tohu reira e kore te mea hāngai hoki werohanga ā-tau i te tarukino. kihai i ārai ia te whanaketanga o te pōauautanga e taea puta i roto i mate viral, me te mate kitakita.

medicament Analogs

"Oseltamivir" - he tarukino tikanga e te mo te maimoatanga me te ārai o te rewharewha. Ko te kaihoko huaketo e pā ana ki inhibitors o neuraminidase. Tenei raau e mohiotia nuitia i raro i te ingoa waitohu "Tamiflu". analogs Structural e kore e tīari reira. Te mahi tata, engari paku iti iho, i te raau taero e whai ake nei he whakakapi, "Relenza", "Arbidol", "Flustol", "Kagocel" me etahi atu.

Reviews, me te aromatawai i te whai huatanga o te tarukino

E ai ki nga hua whakamātautau, i whiwhi nei i roto i te United States me Mexico, ko nga wheori hou tairongo ki inhibitors neuraminidase ( "Zanamivir" me "Oseltamivir"), engari e ātete ki te atu rōpū ratou - adamantanes ( "rimantadine", "Amantadine") .

Me mahara hoki käore te reira e whai nga tohunga kihai i te miramira o tenei tarukino i te maimoatanga o te rewharewha kua tāuta i roto i te iwi ki te ngakau ma'i me mate romahā.

E ai ki nga kaiwhakaako, te whakaiti i te raau taero i te roanga o ngā tohu i te 1 ra, engari ko te take anake, ki te i tīmata te maimoatanga i roto i te torutoru haora tuatahi i muri i te whakapā ki te manawanui tenei.

Ki te rā, kore mōhiohio pono i runga i ranei te pānga o te rōpū o te raau taero i runga i te pā o fifi o mate viral hopuhopu ranei.