Aratohu amlodipine

Medicine "Amlodipine" pea maheni ki maha tuatahi-ringa. Fele, whakaritea tenei tarukino te ki tūroro angina. Kia whakaaro tatou i te tarukino "Amlodipine" i roto i te mōhiohio e whai ake nei ngā tohutohu.

Composition. Kotahi te papa (5 mg) i roto i te kaha besylate taonga amlodipine. Ka rite ki excipients whakamahia reihuka, māngaro potato, collidone, microcrystalline cellulose, konupora stearate.

whakaahuatanga General. Papa "Amlodipine" ma ranei tata ma ki tahi iu-rua. I te tahi taime marama kia marbling reira.

Pharmacodynamics. Dihydropyridine pārōnaki - poraka konupūmā "puhoi" tuarua-whakatupuranga takere he gipotezivnoe me ngā pānga antianginal. E pā ana ki te receptor dihydropyridine me te maua e pā o takere konupūmā, reira whakaiti te transmembrane wahi o katote konupūmā ki te pūtau (ki te whānuitanga nui i roto i te uaua maeneene o taiepa oko atu i roto i myocytes cardiac). meinga pānga Antianginal e roha o te pera me arterioles kei roto i te taha: pakeke umenshaetsnizhaet angina o ischemia myocardial, fakalahi iatuku piringa, reira whakaiti i te tapeke parenga piringa iaia, i roto i āwhina tua ki te whakaiti i te preload i runga i te ngakau, te whakaiti i te ngakau hiahia o te hāora. I roto i te tūroro ki te angina, faarahi te horopeta kotahi rā te wa oma fiznagruzki, pōturi te whanaketanga o te ischemia me angina, me nga mea katoa te whakaiti i te tini o te whakaeke angina me hiahia mo te nitroglycerin. Ko te kupu, tūroro ki angina hiahia tenei tohu "Amlodipine" aratohu.

Pharmacokinetics. I muri i whakahaere-waha o te tarukino te āta whenumi i te wahi gastrointestinal. Pūmau bioavailability toharite ko 64%, te takiwa tino i roto i te serum toto i muri i 6-9 haora. kitea toenga pūmau i roto i te toto i runga i te ra 7. e kore e Food pā te absorption o amlodipine. I roto i te tūroro kaumātua (pakeke ake i te 65 tau) kei te puhoi whakaritea te excretion o te tarukino ki te taitamariki, engari e kore te mea hauora nui tenei rerekētanga.

"Amlodipine" ako e kei te mōhiohio e tika ana katoa kua nga tohu e whai ake nei ki te tono: te takawhita matua (ngā ki te tikanga atu rite ranei monotherapy), angina exertional, angina vasospastic (angina a Prinzmetal).

Contraindications.

- tūtohutanga tiketike ki te whakauru mātātoa me te tahi atu pärönaki dihydropyridine;

- hypotension i roto i te puka nui;

- ru cardiogenic, tiango;

- angina iu (okotahi - angina Prinzmetal);

- hohipera me te hapū;

- kihai i i whakapumautia hoki tangata i raro i te 18 tau o te haumaru me te pānga.

Te inenga me te tikanga o te tono. Tangohia "Amlodipine" ako whakarato e whai ake: roto, te horopeta iti o 5 mg, te mōrahi - 10 mg 1 wa he ra. A, no te taea takawhita horopeta mō te tiaki kia 5 mg ia ra. A, no te riro nga whiu kotahi 5-10 mg ia ra. tūroro kikokore, me te tūroro iti me tūroro ki ate waimaero mahi whakahaere 2.5 mg.

tohutohu Motuhake. I roto i te akoranga o te maimoatanga ki "Amlodipine" kia whai i te taimaha me te kohi o taua matū rite konutai, i ētahi wā e rapu he kai motuhake. He mea nui ki te whai i te akuaku waha, me niho, tirohia te niho wā (ki te karo i te mamae, me te toto pae). Na roto i te whakanui ake i te horopeta i roto i te paari titau aroturuki tupato. Ko te pānga o te raau taero i runga i te kaha ki te pei i te motokā i reira he kahore raraunga. Heoi, kia whanau ai i roto i te ngakau e i roto i te tahi mau iwi e taea ai te whanoke iti, me te momoe.