"Azithromycin" mō ngā tamariki: ako ā-, arotake

I roto i te take o mate faingataa e kore e taea e e rahurahu hāngai paturopi rongoā paturopi, whakahau rata "azithromycin". Hoki ngā tamariki (tohutohu mō te whakamahi e pā ki reira) te tarukino he pānga rawa kaha, i roto i ētahi wā, ka taea e whakapōrearea i kore ano i hanga tino rauropi, na tangohia reira tika pota iti.

puka Tuku me te hanganga

Kei waihanga o taonga kaha me excipients pŭpŭ tauturu azithromycin e e hoatu papa puka tuku iho. Hoki e riro whakawhetai ki enei matū pai tarukino.

Nā ki te rongoā paturopi tūāwhiorangi whanui whakamahi i ngā momo o tuku o te raau taero e whakamahia ana i roto i te Pūtaiao hou:

• capsules koataata Hard ki te tinana taupoki puru, me te puru, i roto i te paura kōwhai ma koma ranei (ranei te papatipu pēpēhia). A, no te pēhi koe te break. E roto i te capsules i roto i te tua ki te whakauru kaha, microcrystalline cellulose, konutai lauryl pūkawa me stearate konupora.
• "Azithromycin" (125) tohutohu mō te whakamahi mō ngā tamariki whakaahua ana rite papa kiriata pani i roto i te puru, i te āhua porowhita, biconcave. I runga i te ringa kotahi i ratou i te whakairo "PLIVA", i runga i te tahi atu - "125". Ki te whati i koe, ka taea e kite koe i e i te tahuri o pire ma. Kei a ia ko te adjuvants e whai ake nei: konupūmā anhydrous hauwai Phosphate, hypromellose, te witi māngaro, microcrystalline cellulose, māngaro pregelatinized, konutai lauryl pūkawa me stearate konupora.
• Drug "Azithromycin" mō ngā tamariki te ako i runga i te tono taunaki ana te puka o te whakatārewatanga, kia taea pharmacies te hoko i te paura motuhake mo tona faaineineraa ki te haunga here panana ranei.

Ko te utu o te piki paturopi i runga i te ihirangi o te taonga hohe rānei.

āhuatanga pharmacological

"Azithromycin" e pā ana ki te paturopi whanui-hihinga. A, no te nohanga nui i roto i te arotahi o te mumura puta te mate o microorganisms.

Te nuinga tairongo ki te tarukino karamu-pai cocci: streptococcus pneumoniae, streptococcus rōpū CF ko G, Staphylococcus pene, St. Pyogenes, St. Viridans, St. agalactiae; Gram-kino huakita: Moraxella catarrhalis, H. Ducrei, rewharewha kukuti, Legionella pneumophila, Bordetella pertussis, Neisseria gonorrhoeae, B. Parapertussis, Gardnerella vaginalis ko Campylobacter jejuni; kaiao anaerobic: Chlamydia trachomatis, Bacteroides bivius, Ureaplasma urealyticum, Peptostreptococcus spp, perfringens Clostridium, Borrelia burgdoferi, Treponema pallidum, ko Mycoplasma pneumoniae. huakita Gram-pai ātete ki te erythromycin, kua tahuri he paturopi ki te puka tautauā.

Pharmacokinetics

"Azithromycin" mō ngā tamariki (tohutohu mō te whakamahi e pā ki reira) te tere whenumi i te wahi gastrointestinal tika ki ātete ki te reo waikawa me te lipophilicity. tohaina tere puta noa te tinana. Ngāwari ô te reira ki te wahi romahā, kiko ngohengohe me te kiri e kore e anake, engari ano hoki ki nga whekau o te wahi urogenital. Ka rite ki te hua, he here iti o te azithromycin me serum pūmua, kătahi kaha ki ngā pūtau eukaryotic me te kukū i roto i te reo ki te pH iti, nui haere lysosomes taiao roanga hawhe-te ora me te kukū i roto i te kopa.

tenei katoa whakatau te rōrahi teitei o te tohatoha (31.1 rita ia kg) me te whakawātea wē tiketike. Hoki te whakangaromanga o tukumate intracellular o ngā faufaa ko te kaha ki te "Azithromycin" kohikohi tika i roto i te lysosomes.

Nā phagocytes whiwhi tarukino ki te pae o te mate, i reira tukua ia i roto i te tukanga o te phagocytosis. I muri 12-72 haora o tango i roto i te arotahi o te mumura tutuki e te kukū tiketike o te tarukino, i te mea tino teitei ake i te kukū inhibitory iti mo te mate o tukumate.

Ka rite ki kua whakahuatia, tukanga roa hawhe-te ora, na, hei tauira, e rapu 60 ki te 76 haora ki te tango i te papanga. Kei te rongoa kukū bactericidal o te tarukino i ngā wāhi o te mumura hoki 5-7 ra i muri i te horopeta whakamutunga, na ko reira taea ki te whakamahi i te rongoā paturopi kotahi i roto i te ra, ko te kore neke atu i te wiki te akoranga o te maimoatanga.

Ngā whakaaturanga "Azithromycin" te nuinga i roto i te ate, me anake te hautanga iti - ka tiana.

Tuhinga mō te whakauru

E akiakitia ana "Azithromycin" tohutohu mo te whakamahi o te tamariki ki te whakaingoa i mate hopuhopu, me te inflammatory, e kua pōreareatanga e huakita i haria ki te azithromycin. Taua mate ngā: kakā, Bronchitis, pakohu kakā, pharyngitis, kiko ngohengohe me mate kiri, tonsillitis, otitis pāpāho, mate Lyme me urethritis. Hoki pediatricians kakā whakapae ahu ki te whakahau tonu paturopi, ara waho nga hua o te whakamātautau X-ray. kia timata maimoatanga o tenei mate i roto i te wa pai, te kore ai koutou kanohi i te mau hopearaa tino meapango. tīpakohia te rongoā paturopi i roto i te take i taua e tango ki pūkete nga tohu katoa, te tukumate kiia me te pikitia haumanu rite te katoa. I roto i te whakatau i te rauropi meinga te mate, tangohia te tau o te tamaiti e ki pūkete. Ki te whakapae kakā te i roto i te tamaiti pakeke 1 ki te 6 marama, ka. tino pea, te māngai - o Staphylococcus pene, i te tau kotahi ki te ono tau - streptococcus pneumoniae. Ki te momo e rua o huakita tōtika whawhai "Azithromycin".

dosing

Ka whakawhirinaki te talena maimoatanga i runga i te mate, engari kia mau tonu te horopeta katoa. kia whakahau i te tākuta te tarukino "Azithromycin" mō ngā tamariki. Tohutohu mō te whakamahi faati'a papa ki te tango i ngā pakeke anake mai i roto i ratou 250 ki te 500 mg o taonga kaha, ka tātai tenei moni kei i runga i te puranga kaua nui. Ko te meka e kia horomia katoa papa, e kore e tūtohu ana ki te kuru i orohina ai reira kia kore e taea e mau tonu i te inenga tūtohutia o te whakamahi kotahi-wā (10 mg / kg) ranei. Ko reira hoki tenei take e taiohi rite āpiha antibacterial whakahaere "Azithromycin" (125). Tohutohu mō te whakamahi mō ngā tamariki papa opani tango ake ki te 12 tau e, e taea te whakakapi ratou ki te tirikara, he whakatārewatanga ranei.

Hoki te maimoatanga o whakapeka mate airway inflammatory, otitis, kakā i whakaritea raau horopeta kotahi (10 mg / kg). Drug "Azithromycin" (125) tohutohu mō te whakamahi mō ngā tamariki i roto i nga papa taunaki e muri anake pa tonu 14 nga tau o te tau. whakamana Treatment tamariki anake te whakamahi i te slurry.

kia whakahuatia te reira i e i roto i te 5 karamu o te tirikara "Sumamed" (tīpune) me ētahi atu waihanga analogs roto hoki 125 mg o taonga kaha. Nä, ko te horopeta paerewa mō ngā tamariki pakeke ko 1-2 punetēpu, i runga i te taimaha rānei. I roto i nga ra e whai ake nei e wha o te maimoatanga tonu, engari i te inenga ano e heke ki te 5 mg / kg. I roto i te take o nui horopeta mate kia rererua, engari i roto i te āhuatanga i taua, ko te whakamahi o te rongoā paturopi he whakaaetia anake i raro i te mātakitaki o te mātanga. Te faaineineraa "Azithromycin" kia te whakamahi (125) tohutohu mō te whakamahi mō ngā tamariki anake i roto i te take o te fariiraa i te kotahi, e rua i te inenga o te 30 mg / taimaha tinana kg.

contraindications

Drug "Azithromycin" mō ā-tamariki ako opani ata whakaaro iti iho i te rima kirokaramu. I tua atu, kua contraindicated reira i roto i te tūroro ki te hypersensitivity ki te wāhanga i roto i roto i te hanganga ki tetahi atu paturopi macrolide. Ko tenei tarukino i roto i tetahi take e kore me te whakamahi i roto i te ate nui, me te hēnga o ōna whatukuhu.

Tuwhena rawa, me te taha pānga

Hoki te hunga mau mama e te whakamahi i te tarukino "Azithromycin" mō ngā tamariki, ngā tohutohu mō te whakamahi (mua manawanui e pā ana ki te whakamahi o paturopi aroaro i roto i tenei rauemi) whakarato te rārangi o ngā pānga taha. I runga i te wahi o te pūnaha, me te toto hanganga lymphatic kia whakawhanake trombotsipenii.

Tūroro kitea fakaaoao, te totoa, pau te me te manukanuka. Mai i te pūnaha io Whanoke, haehae, ānini, somnolence, a tae noa whiti nga. I roto i te wā onge, te raau taero ai mataaratanga, rohirohi, paresthesias, ohorere hoki tirohanga o kakara, me te reka.

Pinepine macrolides (rōpū o taero, te pūtake o te hanganga matū o e protrude mowhiti macrocyclic 14 ava'eo ranei 16-membered lactone ki te toenga warowaihā piri), me e no ki "azithromycin" arahi ki rongo mate. Varavara, engari tonu i reira he pānga taha o te huru dyspeptic me kitea tauhohe mate pāwera.

"Azithromycin" ako i runga i te tono e āhei ngā tamariki ki te whakamahi i, engari e taea te tango tamariki raau anake i roto i te puka o te whakatārewatanga. Hoki ngā tamariki pakeke pai me te puka capsule o te rongoā paturopi. I mua i te tono i te rongoā, e hiahia ana koe ki te whiwhi whakaaetanga o te tākuta, me te āta pānui i te tohutohu mōkihi whakauru.

Mō kia tohu korere tuwhena rawa, rangitahi mate rongo, whakapairuaki, me te ruaki. I roto i te take o rawa nga pota taunakitia me horoi tonu puku, ka puta ki te therapy symptomatic.

Ara

Ko te whakamahi o "Azithromycin" i roto i te hapū, ko te tino houhou, engari e manakohia ki te kore e taea ki te whakamahi i te reira ki te āwhina i te wahine (pānga tarukino i runga i te whanaketanga fetal i 100% kua kore i ako). Ko te wā hohipera ka whakamahia i te wa o te maimoatanga rongoā paturopi ki te aruaru whāngai ū.

Tamariki i raro i 12 tau he pai ki te whiriwhiri i te tairitenga "Azithromycin".

Inu waipiro e kore e pā te mahi o te raau taero, Heoi hanga ona whakamahi te hoki tetahi mate. Na reira, tūtohutia te nui o waipiro pau te ki te whakaiti ki te mōrahi, ka tae noa pai ki te hoatu ki runga i runga i te maimoatanga tino.

taunekeneke tarukino

Ki runga ki te fariiraa i te "Azithromycin" ki te waikawa e roto i konupūmā, konupora me te konumohe, pōturi reira te absorption o te rongoā paturopi, reira, e tika ana ki te mau i te wā 2-haora i waenganui i pota o enei taero.

Ko te rerekētanga matua i waenganui i tenei tarukino ki ētahi atu paturopi macrolide - kahore kōrero ki te pūnaha cytochrome. Na reira, ka riro ki "theophylline", "carbamazepine", "Digoxin", "terfenadine" me "triazolam" i reira kua kore pāhekoheko.

Ki te whakamahia te tarukino te ki "warfarin", he mea e tika ana ki te aroturuki i te wa prothrombin.

Lincosamides whakaiti te whai huatanga o te rongoā paturopi me chloramphenicol me tetracycline nui haere.

Here me ngā

kia penapena i te rongoā paturopi i roto i taea o ngā tamariki i te pāmahana ki runga ki te 25 nekehanga. I runga i te ora papa o taunakitanga e wātea ana ki te tarukino "Azithromycin" (mō ngā tamariki), ako ā-ringa. Ka taea te rongoa te whakatārewatanga rite hoki kaua e nui ake 5 ra, te paura ano - 2 tau, me papa me capsules - ki runga ki te 3 tau.

Analogs me whakaaro o tūroro

Ko te hunga e whakamahia te "Azithromycin" mō ngā tamariki (tohutohu mō te whakamahi e kore e tūtohutia nga capsules ki te tango i roto i ngā tamariki), mahue arotake te nuinga pai. I muri i te horopeta tuatahi o te whakapai ake nui taratahi paturopi, ahu atu.

Na roto i te analogues o te tarukino ngā "Azitsin", "Zomax," "Sumamed", "Azitral", "Azaks", "Zitroks" me etahi atu.