Mate huka pākawa: take, tohu, te tātaritanga, maimoatanga

I roto i te ao i teie mahana tata e mōhio o tenei mate, kia rite ki kōiwi matua katoa. I runga i te hiahia mo te ārai o tenei mate ārai tākuta te o ia tamaiti i roto i te tuatahi o nga marama o te ora o te tamaiti. Kōiwi pā ana ki mate whiwhi whakawhanake tika ki iti cholecalciferol - he taonga e mohiotia ana ko huaora D.

Heoi, i roto i ētahi wā i roto i ngā tamariki rawa taitamariki i tohu o te mate, ahakoa i te pipiki ki āraihia. I roto i te take taua kia whakapae mate pērā i te mate huka Phosphate. Rerekē kōiwi, pā ana te mate ki pathologies ira. Na reira, ko te reira mate atu kino, me te rapu utu i te maimoatanga roa matatini.

He aha te mea te mate huka Phosphate?

Na ko te rōpū o mate ira e pā ana ki pākia kohuke waimaero. I roto i te tahi atu māuiuitanga i huaina huaora kōiwi D-ātete. momo tino o te mate huka Phosphate puta i roto i pā ana ki 1 tamaiti i roto i o 20,000 tamariki whanau hou. i whakaahuatia tuatahi te mate i roto i te tau 1937. I muri ka tahuri te reira i roto i taua i reira e te tahi atu mau huru o abnormalities ira. Nuinga o ngā wā, kitea huka Phosphate te i roto i te kōhungahunga. E rata ana te reira i te aro o te mau metua kiwi e ngangau me te āhua o te wheua.

E haere tahi ētahi momo o te mate e te tahi atu disorders pūkoro tinana. I te tahi taime he asymptomatic te mate, a taea anake tautuhi i te reira e te whakamātautau taiwhanga. whakarōpūtia te mate i te kōiwi riro, hypoparathyroidism me ētahi atu abnormalities endocrine. kia integrated maimoatanga i te wawe tau.

Ko te take o te mate

Ko te take tuatahi o te mate huka Phosphate ko te pakaru i roto i te hanganga ira. E riro irakētanga. Carriers o te ira rerekē e taea e rua wahine me te tangata. Puta ana te irakētanga i roto i te X-pūira hono, i te mea ngoi. I roto i te wā onge, e taea te riro mate huka Phosphate. whakawhanake ia i roto i nga puku o mesenchymal kikokiko, i hanga i roto i te utero. I roto i tenei māuiuitanga i huaina ko "kōiwi oncogenic."

e pā ana te mate ki te tubulopathy rōpū - disorders o nga whatukuhu. No te mea kohuke heke reabsorption i roto i te tubule proximal, te whakawhanake i tētahi hē o ūkuikui i roto i te tinana. I tua atu, i whakaohooho whēkau momi kaha. Ka rite ki te hua, i reira he huringa i roto i te hanganga kohuke o te kiko wheua. He maha he takahi o osteoblast mahi. Tangata haere ira pathologically rereke tamahine anake, me nga wahine - tamariki a tane e rua. Ka rite ki te tikanga, te atu nui mau tamaroa te mate atu i roto i te mau tamahine.

Whakarōpū o mate huka Phosphate i roto i ngā tamariki

He maha ngā momo o te mate, rere i roto i paearu ira, me te haumanu. Nuinga noa pāngia kōiwi hypophosphatemic X-hono, e kua he tauira tino o te tupu. Heoi, i reira e te tahi atu momo o te māuiuitanga. Ko te whakarōpū ngā te ahua e whai ake nei o te mate:

1. mate huka Phosphate momo tino X-hono. Kei te āhuatanga i te reira e te huringa PHEX ira, e encodes te endopeptidase. Tenei whākōkī te kawenga mo te transportation o ngā kohuke i roto i te tākihi me takere katote intestinal. No te mea pōturi tenei tukanga irakētanga ira iho, hoatu ara ki te kore e katote Phosphate i roto i te tinana.
2. X-hono ngoikore. Te āhuatanga irakētanga CLCN5 o te ira e encodes he pūmua kawenga mo te mahi o takere māota katote. Ka rite ki te hua o te koha fakahohaasi transportation o matū i roto i te membrane o te tubules tākihi. Carriers o tenei momo o te māuiuitanga e taea e rua wahine me te tangata. Heoi, puta te mate anake i roto i te mau tamaroa.
3. tauira tino Autosomal o mate huka Phosphate. Kei te whai pānga te reira ki te irakētanga ira i roto i te pūira 12. No te mea osteoblasts koha pathological he pūmua taratahi e whakatairanga whakarei tango Phosphate i te tinana. huru no te māuiuitanga e ngā ngawari, rite te ātete ki te puka X-hono.
4. Autosomal ngoikore. Rare. Kei te āhuatanga DMP1 ira i roto i te pūira 4. encodes reira he pūmua e te kawenga mō te whanaketanga o te wheua, me te dentin.
5. Autosomal ngoikore, tahi e te tukunga o te konupūmā i roto i te mimi. Whakatika hoki kei te koha ira i runga i te pūira 9 me te tiaki o nga awa tākihi konutai-ti'aturi.

I tua atu ki enei momo o mate huka Phosphate, i reira e te tahi atu momo o te māuiuitanga. Ētahi momo o te mate e kore i ako noa nei.

Rerekētanga i waenganui i kōiwi me te mate huka Phosphate

Kōiwi me mate huka Phosphate i roto i ngā tamariki - e kore ko rawa te mea ano tenei, ahakoa ko tata ōrite te pikitia haumanu o te mate. Ko te rerekētanga i waenganui i enei pathologies i roto i te etiology me te huarahi o te whanaketanga. kōiwi noa - riro te reira mate e pā ana ki te kore o te cholecalciferol. hua ana tēnei taonga i roto i te kiri i raro i te mana o te rā. hanga horopeta Tātaritanga o te huaora D kei te ki te tango i runga i te rā ki ngā tamariki katoa i te 1 marama ki te 3 tau, hāunga raumati. Nā ki te kore o te cholecalciferol ohorere tukanga mimititanga konupūmā. Ka rite ki te hua o te whakawhanake wheua deformation.

Rerekē te mate huka Phosphate ko reira e pā ana te reira ki te mate congenital. A, no te whakaohooho tenei māuiuitanga absorption o ngā kohuke i roto i te tākihi, i roto i ngā - i te phosphates. I roto i ētahi wā, i reira he konupūmā hē. Nā ki maumaui o te hanganga kohuke o pathologies wheua kikokiko ano he tohumate. Ka taea te whakapumautia te rerekētanga i waenganui i a ratou i muri i anake te tātaritanga taiwhanga.

kōiwi Hypophosphatemic i roto i nga kohungahunga: tohumate

Tohu o te mate e te nuinga o pāngia i roto i te rua o nga tau o te ora. I roto i te wā onge, i reira he kōiwi hypophosphatemic i roto i nga kohungahunga. Tohu e taea te pāngia i roto i te aruaruraa - he hypotonia me alangá shortening uaua. Ko te mau faaiteraa haumanu matua ko:

1. Deformation o te hononga iho waewae.
2. curvature o nga topito o raro e-āhua.
3. Growth retardation i roto i ngā tamariki - riro kitea i muri i te 1 tau.
4. Thickening o te ringa me te rara wheua ngohe - "poroporo rachitic me pirepire."
5. Mamae i roto i te wheua o nga papatoiake me tuarā.
6. Tūkino o niho i tohu.

Nuinga o ngā wā i te amuamu matua o nga matua, ko e kei te piko waewae o te tamaiti. Ki te ahunga whakamua o te mate i reira ko te tamarûraa o nga wheua - osteomalacia.

Tātaritanga o te mate huka Phosphate me kōiwi

Ki te kitea abnormalities, whakahaere he ako o te hanganga matüora o toto. Kei te kï hoki, hypophosphatemia. te taumata o te konupūmā i roto i nuinga o te wā noa, ētahi wā - heke. I te teitei o kōiwi reira ko te hua o te phosphatase kawakore. A, no te whakakitea X-hihi osteoporosis me tupu wheua rohe ofatiraa. I roto i te mimi tohu te nui nui o phosphates. I te tahi taime i reira he konupūmā mimi.

Treatment o kōiwi, me te Phosphate huka

whakamahia hoki te maimoatanga o te mate huka Phosphate pota nui o cholecalciferol. I roto i ētahi wā, whakaaturia tāpiringa konupūmā. Kia tino ki te whakamahi i ngā rongoā kei roto ūkuikui. Ki te whakapai ake i te huru o whakaritea tāpiringa huaora me te kohuke. Ēnei ngā te "Vitrum" taero "Duovit", "Alphabet" me pera i runga i. D.

A, no te whakaaturia curvatures whakahuatia o wheua i tua, therapy tinana me te pokanga. Me kōrero te podiatrist.

āraihia atu me matapae

Hoki te ārai mehua ngā arowhai tākuta tamariki me te taote, he haere i roto i te rangi hou, i te whakarite o te huaora D i o te ora tuatahi te marama. Ki te hunga e mate o Phosphate huka te whānau kia amohia e whakamātau ira i roto i te utero kukune. Matapae te nuinga pai ki maimoatanga wā.