Medicine 'MabThera'. Tohutohu mō te whakamahi

Ko te kāwai o taero anticancer ngā tarukino "MabThera". Whakaahuatanga medicament tohu tona kaha ki te herea āta ki te transmembrane antigen hakari i roto i 95% o te lymphomas kore-Hodgkin o, puka B-pūtau. wāhanga hohe - rituximab.

Medicine "MabThera". Tohutohu: iteraa papû

Rongoā whakaritea hoki lymphoma B pūtau-kore-Hodgkin o:

- himioustoychivoy recurrent ranei, CD20-pai ki iti-māka follicular ranei;

- te toru ranei te wha follicular atamira i roto i ngā ki te hahau i roto i te tūroro e kore kitea i mua ki te maimoatanga;

- i muri i te whakautu follicular ki therapy arataki rite he tikanga tautoko;

- CD20-pai B-nui-i roto i ngā ki kaupapa tapatapahia rawatia hahau.

Tikanga tūtohutia "MabThera" ā-ringa mō te kanisā lymphocytic ma'i :

- i roto i ngā ki te hahau i roto i te tūroro e kore kua waiho i raro ki te maimoatanga paerewa;

- recurrent himioustoychivom ranei i roto i ngā ki te hahau.

Medicament whakaaturia pakeke ki te ahua kaha o te kaikōiwi i roto i ngā ki te medicament "MTX" takarepa ka tono urupare hypersensitive regimens whakaora ranei.

contraindications

e kore te tūtohu te tikanga "MabThera" ako, ki te he hypersensitive koe.

Me whakararu tūpato ina whakahaere taero ki tūroro ki arrhythmia, angina, kore ngakau congestive, pēhanga toto tiketike iti ranei, thrombocytopenia, neutropenia, COPD (e tika ana ki te tūponotanga o te takanga o te bronchospasm).

pānga taha

I roto i te tono i te tarukino "MabThera" Kia meinga whakapairuaki, mamae puku, ruaki. ngā ano nga mau faaiteraa tōraro hypotension orthostatic, arrhythmia, tachycardia, bradycardia, waimaero o te mahi tākihi, edema piringa, mamae i roto i te pouaka me te rohe tuaiwi lumbosacral. Ko te tarukino "MabThera" Ka taea e meinga piringa neuropathy, neuritis, te momoe ranei ohoroa, rōpū, whārua ranei, manukanuka, ngoikore, whanoke, mamae i roto i te upoko. ngā kino whakaaro ki te waiho i te tauhohenga pāwera. Ko te tauhohe kino ka whakamahi i te tarukino "MabThera" tohutohu he Rhinitis, pharyngeal edema arero ranei, hāhā o te manawa, bronchospasm, kiri oranga, taimaha tinana iti, te whakararuraru o reka, tremors, Chills, kirika, te mamae i roto i te rohe kaki, me te ki te pae o te localization puku, te whanaketanga o te herpetic mate.

inenga

whakahaere ana te raau e whaowhia rō-uaua puhoi. A, no te whakamahia monotherapy te kotahi te wiki i runga i 375 mg mō te wha wiki. Ko te auau tuatahi o te whakahaere tuatahi o te 50mg / h. Te whakanui ake ki te mōrahi (400 mg / h) kuo pau ke auau āta.

Ara

E toru tekau ki ono meneti i mua ki te whakahaere premedication (faaineineraa) ki Pë me taero antihistamine tūtohu.

I roto i te therapy, a i roto i nga marama kotahi tekau ma rua i muri i me te whakamahi i te otinga o nga wahine o te whanautanga tamariki tau ārai pono.

kia mutu taero Antihypertensive kotahi tekau ma rua i te iti rawa haora i mua i whakahaere o te tarukino "MabThera".

Ehara i whakapumautia miramira me te haumaru o te tarukino i roto i ngā tamariki.

I te faaineineraa "MabThera" fakamatala i te tohunga te nuinga pai. Ano, i roto i te akoranga o ngā tirohanga, ka kitea taua mea e te tikanga te whakarite tonu o te tarukino rite te monotherapy, me te te whakamahi muri o reira rite te tautoko mō te rua tau Whakahekea te tūponotanga o te ähua o te lymphoma follicular.