Rārangi o raau taero antiarrhythmic me ratou whakarōpū

Tata ite tūroro katoa ara mafatu ranei tetahi ki rerekē momo o arrhythmias. I tēnei wā, tuku te ahumahi ho'oraa he whānui o māngai antiarrhythmic momo. Ratou whakarōpū me ngā āhuatanga kōrero i roto i tenei tuhinga.

ara o te rongo

Hei whakatau i arrhythmias cardiac mōwaho, kua whakaritea āpiha antiarrhythmic. hāngai ana te tikanga o te mahi o taua raau taero i te mahi āhuatanga electrophysiological myocardial o ngā pūtau:

• Whakaiti i te tere o te pūmanawa mahi, ai tērā kawenga o excitation.
• Ko te hekenga i roto i te excitability o te myocardium.
• Whakaiti i te wa te tutu whanaunga, hua i roto i te shortening o te wā, ka taea te hihiko faahiahia tīmata hukihuki cardiac.
• Elongation whai hua wā whakangutungutu, i te mea nui ka tachycardias me mo te whakakore ngātere e puta i muri i iti rawa te wa i muri i te whakaiti tino arotau.
• auau Raukaha o te excitation e whakatairanga homogenization me ārai te āhuatanga o te re-urunga ( «re-urunga").
• Inhibition o ruma mōwaho automatism hono e te ki te toronga o te wā o te depolarization diastolic.
• Whakakore rerekētanga i roto i te tere o te excitation me ngā tohu refractivity.
• Heke te tūtohutanga cardiac ki rere hiko me te mōrea o te ventricular fibrillation.

Whakarōpū o raau taero antiarrhythmic

E wehea nga rongoa katoa i roto i tenei rōpū ki ngā akomanga wha. I tua atu, wehea te piha haapiiraa tuatahi e atu ki toru subclasses. hāngai ana tēnei whakarōpūtanga te i runga i te whānuitanga o te pānga tarukino i runga i te kaha o ngā pūtau ngakau ki te kawe i te hanga me te kawenga o tohu hiko. akomanga rerekē o taero antiarrhythmic i ratou ara o te rongo, na i roto i ngā momo rerekē o arrhythmias ka rerekē ratou whai huatanga.

Ko te piha haapiiraa tuatahi ngā te blockers hongere konutai nohopuku. IA piha ngā taua raau taero rite "quinidine" "Dizopiramid", "novokainamid", "Giluritmal". E IB sublcass hipokina "Piromekain", "tocainide", "Difenin" "Lidocaine", "aprindine", "Trimekain", "Mexiletine." Sublcass IC hanga taputapu pērā i "Etmozin", "Ritmonorm" ( "Propafenone"), "VFS" "Etatsizin", "Flecainide", "Indekainid", "Bonnekor", "Lorkainid".

Kei te piha haapiiraa tuarua o te beta-blockers ( "metoprolol", "nadolol," "alprenolol," "Kordanum", "Propranolol", "acebutolol", "Pindolol", "Trazikor", "Esmolol").

toru o te piha haapiiraa ngā blockers hongere pāhare pāporo "tosylate bretylium", "Amiodarone", "Sotalol".

te wha o nga piha ngā blockers konupūmā hongere puhoi (hei tauira, "Verapamil").

e kore e Rārangi o taero anti-arrhythmic mutu ki reira. He hoki kai glycosides cardiac, konurehu pūhaumāota, konutai triphosphate, konupora pūkawa.

Rongoā Class Tuatahi

mutu blockers Konutai hongere tuku nohopuku i roto i te pūtau o te konutai, e ai retardation o te wahi o te roangaru myocardium excitation. Na roto i tenei Katohia tikanga mo te tohanga tere i roto i te ngakau o tohu pathological, ka tonu arrhythmia. Kia whakaaro tatou te rōpū o taero antiarrhythmic no ki te piha haapiiraa tuatahi.

Rongoā Class Tuhinga

taero Antiarrhythmic taua whakaritea i extrasystole (ventricular me supraventricular) me ki whakahoki pakohu manawataki roto i te take o te fibrillation Atrial (fibrillation Atrial). I tua atu, kei te whakamahia ratou ki te ārai i whakaeke recurrent.

"Procainamide" me "quinidine" - whai hua raau taero antiarrhythmic ki tachycardia. Ka korero matou ki a koutou ake e pā ana ki a ratou.

"Quinidine"

whakamahia tēnei rongoā i roto i te take o paroxysmal tachycardia supraventricular, me te i roto i te paroxysms o fibrillation Atrial ki pakohu manawataki. Nuinga o ngā wā, faaterehia te rongoā i roto i te puka o papa.

Paihana taero antiarrhythmic uaua tupu, engari ka fariiraa i "Quinidine" pānga taha taea pērā i raruraru kūnatu (ruaki, korere), me pāhoahoa. I tua atu, e taea ki te meinga i te hekenga i roto i ngā taumata toto mōtepe, intracardiac āriponga tērā, te whakaiti contractility myocardial te whakamahi o te tarukino ko. Ko te pānga taha tino mōrearea - te whanaketanga o te ventricular tachycardia, he puka motuhake, e taea meinga mate ohorere o te manawanui. Ko e 'uhinga maimoatanga "quinidine" kia kawea i roto i anake ki te mana o ECG me i raro i te mātakitaki o te mātanga.

contraindicated te rongoā i roto i intraventricular me atrioventricular poraka, haurangi glycoside cardiac, thrombocytopenia, hypotension, kore ngakau congestive, hapūtanga.

"Procainamide"

He te taua tohu mō te whakamahi rite "quinidine" tenei tarukino. Tino maha te whakaritea ai mo te whakaaro o te te tauturu o te fibrillation Atrial paroxysmal. A, no te werohanga rō-uaua "novokainamid" taea whakaiti koi i roto i te pēhanga toto na te mea e tika ana ki te whakauru i ko āta mōrahi te otinga.

I roto i te pānga taha wehewehe whakapairuaki, ruaki, huringa i roto i te toto, disorders o te pūnaha io i roto i te puka o te whanoke, ānini, i roto i ngā take onge, te whakama. Ki te te whakamahi o te aumou tarukino, kia whakawhanake i syndrome lupus-rite (serozity, rumati, kirika), mate koiora i roto i te kōhao-waha, tahi e te patunga whakaora puhoi me mariao, me te toto pae. I tua atu, "novokainamid" taea whakapataritari he tauhohenga pāwera, i roto i tenei take, ka waiho i te tohu tuatahi o te takanga o te uaua ngoikore i roto i te faatereraa i te tarukino.

Hoatu te rongoā rāhuitia te ka poraka atrioventricular, nui täkihi me te ngakau, hypotension me te ru cardiogenic.

piha IB

Taua raau taero i iti pānga i runga i te pakohu kōpuku, hononga atrioventricular me te marae, na whai hua i roto i te take o arrhythmias supraventricular. Whakaritea e te raraunga taero antiarrhythmic ki arrhythmia, tachycardia paroxysmal, arā, mo te maimoatanga o arrhythmias ventricular. Kei te whakamahia hoki ratou ki te hamani arrhythmias, e kua pōreareatanga e te tuwhena rawa o glycosides cardiac.

Rārangi o raau taero antiarrhythmic i roto i tenei piha ko tino whānui, engari te tikanga "lidocaine" whakamahia te tino maha. Tikanga, kua whakahaerea reira e pâmuhia i take o arrhythmias ventricular nui i roto i te t. H. I roto i te infarction myocardial.

taea ki te whakapōrearea i te mahi o te pūnaha io, whakakitea nei te whanoke, hukihuki, raruraru ki te kupu, me te kite disorders o mahara "Lidocaine" ko. Ki te whakamōhio tatou te tarukino i roto i pota tiketike, kia pōturi te auau ngakau, heke contractility cardiac. Ano, e pea ki te hanga i angioedema, urticaria, pruritus tauhohe mate pāwera.

contraindicated "Lidocaine" Kei roto i te poraka atrioventricular, e mate ana syndrome pakohu. e kore te rongoā tohua i roto i te take o te nui arrhythmias supraventricular no o nui ake te mōrea o te fibrillation Atrial.

piha IC

Drugs no ki tenei piha haapiiraa, whakawhānui āriponga intracardiac, ngā i roto i te pūnaha tana-Purkinje. E ratou āhuatanga kaha arrhythmogenic, na inaianei ratou whakamahinga he iti.

Kua Rārangi o taero antiarrhythmic o tenei piha kua hoatu i runga, engari kei te tikanga e whakamahia ana "Propafenone" ( "Ritmonorm") anake. Kei te tohua te reira no te arrhythmias supraventricular me te ventricular, i roto i te Vol. H. raro SVC syndrome. Mai i reira he he tūpono o ngā pānga arrhythmogenic, me te whakamahi i te rongoā i raro i tākuta mātakitaki.

I tua atu ki te arrhythmia, Ka taea e tenei tarukino meinga ahunga whakamua o te kore ngakau, me te ähua o te contractility cardiac. I roto i te taha e taea pānga e taiea reka ahua konganuku i roto i te mangai, whakapairuaki, me te ruaki. E kore e araia te reira i taua pānga kino, pērā i te kite te peroo, huringa i roto i te whakamātautau toto, whanoke, ohoroa, whārua.

Beta-blockers

A, no te faarahi te āhua o te pūnaha io pukuaroha, hei tauira, i roto i te take o te ahotea, takawhita, disorders autonomic, ischemia, i roto i te toto, i reira he tokomaha o catecholamines, tae atu Adrenaline. mahi ēnei matū i runga i receptors beta-adrenergic o te myocardium e tika ana ki te tapepe hiko cardiac me te ahua o arrhythmias.

Beta-blockers ārai whakaongaonga nui o receptors me reira tiaki te myocardium. I tua atu, whakaiti ratou te excitability o nga pūtau o te pūnaha kawenga, e arata'i ki te beat ngakau puhoi.

Rongoā o tenei piha e whakamahia i roto i te maimoatanga o te kaka e Atrial me fibrillation Atrial mo te ārai me te awhina o arrhythmias supraventricular. I tua atu, te āwhina ratou ki te hinga tachycardia pakohu.

Whakaaro taero antiarrhythmic hua mo te fibrillation Atrial, ki te haunga o te wā i reira meinga te māuiuitanga e te taikaha o komuhumuhu catecholamines.

Kei te maha "Metoprolol" me "Inderal" whakamahia mo te maimoatanga o arrhythmias. Ēnei taero i pānga taha pērā i tērā auau ngakau, whakaiti contractility myocardial, ahua poraka atrioventricular. Ka taea e ēnei rongoā tīmata pito matao, me te ähua o te rere toto piringa. I tua atu, pā te raau taero te pūnaha io, meinga te momoe, whanoke, korekore, mahara waimaerotanga. huri ano ratou i roto i te kawe o te raru, me uaua, whakakitea nei e ngenge me te ngoikore.

E rāhuitia Beta-blockers i te whakamahi i roto i te ru cardiogenic, edema pūkahukahu, taiāki huka ririki, huangō. Hoki protrude contraindications poraka atrioventricular o te tuarua, pakohu bradycardia.

blockers pāhare pāporo hongere

Ko te rārangi o raau taero antiarrhythmic i roto i tenei rōpū ko nga tikanga retarding tukanga hiko, me te reira ārai takere pāhare pāporo i roto i ngā pūtau cardiac. Ko te rongonui tino o tenei piha o rongoā - "Amiodarone" ( "Kordaron"). I roto i te tahi atu mea, mahi ai i runga i nga receptors M-holino- me adrenergic.

"Kordaron" te whakamahia hoki te maimoatanga me te ārai o te ventricular, Atrial me arrhythmias supraventricular, raruraru manawataki ngakau i runga i te whakamārama o SVC syndrome. Kei te whakahaerea ano te medicament i roto i te tikanga ki te ārai arrhythmias ventricular ora-te whakawehi i roto i te tūroro ki te myocardial whakapeka. I tua atu, kei te whakamahia te reira ki te whakaiti i auau ngakau i fibrillation Atrial tamau.

Ki te whakamahi koe i te taputapu mo te wa roa kia whakawhanake interstitial kakakīrehe pūkahukahu, huringa o te tae kiri (te ahua o te hue papura). I roto i ētahi wā, pāhoahoa, moe disorders, mahara, me te kite. Reception "Amiodarone" pea te take o te pakohu bradycardia, kōroke, whakapairuaki, me te ruaki.

Kaua e whakahau rongoā i te bradycardia tuatahi, QT roa, takahi o te pūkawe intracardiac, mate thyroid, hypotension matua, hapūtanga, huangō.

blockers Calcium hongere puhoi

Enei taero kawe te raka konupūmā puhoi nāianei, reira tāmia te aronga mōwaho i roto i te atria me pakohu kōpuku automaticity iti. Ko te rārangi o raau taero antiarrhythmic i roto i tenei rōpū ngā "Verapamil," whakaritea nei mo te ārai me te awhina o tachycardia supraventricular paroxysmal, supraventricular therapy arrhythmia. "Verapamil" he whai hua i roto i te take o arrhythmias ventricular.

pānga te taha ngā poraka atrioventricular, pakohu bradycardia, hypotension, a i roto i ētahi wā - te whakaiti i te kaha contractile o te ngakau.

glycosides cardiac

e kore e e oti Whakarōpū o taero antiarrhythmic kahore te whakahua o enei moni. Ēnei ngā taero pērā i "Tselanid", "Korglikon", "Digitoxin", "Digoxin" me etahi atu. E whakamahia ratou ki te whakahoki pakohu manawataki, tachycardia supraventricular, whakaiti o te auau ventricular i te take o te fibrillation Atrial. A, no te whakamahi i glycosides cardiac whai ki te aroturuki i tō huru. Tohu o te digitalis haurangi whakakitea e puku mamae, whakapairuaki, me te ruaki, pāhoahoa, atarua me te moe, te toto i te ihu.

Kei te riria te reira ki te tono i enei taero antiarrhythmic i roto i bradycardia syndrome ERW intracardiac pā. e kore e ratou whakaritea i roto i te take o tachycardia ventricular paroxysmal.

antiarrhythmics pahekotanga

Ki te ungeri mōwaho i roto i te mahi haumanu, etahi huinga o taero whakamahia. Ko te kupu, "Quinidine" kia te whakamahi i roto i te taha ki te glycosides cardiac mō te rongoā arrhythmia tamau. Ki te beta-blockers "quinidine" taea te whakaritea kia whakaorangia o arrhythmias ventricular whakangutungutu ki ētahi atu maimoatanga. Ko te whakamahi ngā o beta-blockers me glycosides cardiac homai he pānga pai i roto i te ventricular me arrhythmias supraventricular, me te āwhina ki te ārai i te hohokitanga o tachycardia mōwaho me te tachyarrhythmia.