Macrophages - he aha te mea tenei?

Macrophages - he aha te taua mea? Ranei hanganga? He aha e ratou kawenga i roto i to tatou tinana? Ka enei, me te he maha o enei take, me te kia whakahoki i roto i te tuhinga.

mōhiohio whānui

phagocytes Mononuclear (ranei macrophages) - ko te rōpū o ngā pūtau roa-ora e te hunga nehenehe o phagocytosis. E ratou he rota tonu o ngā āhuatanga noa e hanga rite ratou ki neutrophils. Ka rite ki macrophages - he mātātoa te whai wāhi i roto i te whakautu inflammatory me ārai matatini, te wahi mahi ratou rite ngā pūtau secretory. Me pēhea ratou e mahi? Macrophages, rite neutrophils i diapedesis waiho te bloodstream ka tīmata ki te haere i runga i tona ara - ki te porotītiti i roto i te toto. Ko e whakahaua ratou ki te kopa. I muri i taua i reira ko te huringa → macrophages monocyte. A i te wahi o te taenga, ka mahi ratou o ratou mahi motuhake, e whakawhirinaki i runga i te wāhi kikokiko. E pā ana te reira ki te ate, pūkahukahu, wheua wheua, me te kōateate. I roto i a ratou ka mahi ratou i roto i te tango o matūriki kino me microorganisms i te toto. I roto i taua taea ratou "tahuri"? pūtau Kupffer me mikroglievskie, macrophages kauae, macrophages, kōateate, taikiri, wheua wheua - e te aha e puta ratou.

mahi

I macrophages, kua whakaritea ngā mahi matua e rua o te tinana ki a whakamana e momo rerekē:

1. Whakakore antigens corpuscular. Kei te whai wāhi te reira i roto i na-ka karanga "ngaio" macrophages.
2. Absorption, tukatuka, me te whakaaturanga o te antigen ki ngā pūtau T. E whakamana ana ēnei mahi kua AIC. Kei te whakamahia i tēnei whakaiti tika ki te ingoa roa o te kaupapa moroiti - pūtau antigen-whakaatu.

A, no te te hinu wheua wheua o promonocyte i hanga hanganga pakeke ko rawa he rota o ratou hinga (ka noho i reira) i roto i lymphocytes. Macrophages wa roa mahi ratou taumahinga tika ki te meka i he reira ngā pūtau roa-noho pai kua e whakawhanakehia pungaraungao me taratara kiriuwhi.

Ētahi atu kōrero mō te mahi

Na e matau ana tatou e, rite neutrophils, waiho macrophages te bloodstream ka timata ki te mahi i etahi mahi. I roto i te whānui, me te tikanga matou kua kōrero kē. Na kia whai whakaaro o te fakamākukanga neke atu i te mahi ratou. Ko te kupu, whakarato ratou phagocytosis, hua whākōkī, pūmua, sera, prostaglandins, Radicals hāora, cytokines, leukotrienes. I tua atu, kei te whai wāhi hoki macrophages me secretion o protease kūpapa, hydrolases waikawa, lysozyme, arginase, he plurality o inhibitors pūmua whākōkī, nucleoside me cytokines. hua hoki te whakawhetai ki a ratou e te momo hāora urupare, waikawa arachidonic. Na macrophage - ko reira he take whakahohe chemokines mōtepe. Me kï hoki ratou tūranga i roto i te whakangaromanga o ngā pūtau puku, me te whakangaromanga o pirinoa intracellular. I roto i te whakamutunga, ko te tino nui to ratou tūranga. Ka taea e Macrophages hanumi ki pūtau nui e te hunga i raro i te mana o anti-huripari tahuri ki granulomas. pā taua ngā te nui o kama interferon hua.

tūranga ārai

Otiia tonu te aro rahi kia utua ki te whawhai ki hātare, huaketo me huakita e te tīariari i roto i te pūtau ope. Whakatinana Ko e tika ana ki te aroaro o tikanga bactericidal nohoia e te macrophages. arata'i tenei ki te meka e he ratou tetahi o nga taputapu tino kaha o te wātea i te mate hohonu. Otiia e kore e katoa te e. E tahi ratou i roto i te T me e whai wāhi lymphocytes B i roto i te whakautu ārai. I tua atu, e kore e taea e kore ki te mōhio i te tūranga o macrophages i whakaora maru ia, whakakorenga o ngā pūtau e kua ra io ratou ake, a i roto i te hanganga o whakatū papa atherosclerotic. Ratou kai mooni āhuatanga kino i roto i to tatou tinana. Tenei ratou ingoa noa. Ko te kupu, i roto i te translation Russian o "macrophage" - ". Tangata e kai ana nui" he A kia tuhia te reira e he tino rawa nui enei pūtau.

He aha e nga momo o macrophages?

No te mea tiro tatou mātauranga he phagocytes kiko, i roto i ngā wāhanga rerekē o te tinana ka taea e koe te whakatau i te momo o "whakarerekētanga". Ki te whakaaro tatou tino mea katoa, e te reira te rota o te wā, ka pena ka waiho te arotahi ki runga i te māngai tino nui, pēnei i:

1. macrophages kauae. E whai wāhi ana ratou i roto i te pukapuka, me te purenga o te rangi hau e ngā pollutants kino me matūriki.
2. pūtau Kupffer. E tū ana i roto i te ate. Te nuinga rave i roto i te whakangaromanga o ngā pūtau toto tawhito.
3. Gistotsity. ora ratou i roto i te kopa tūhonohono, kia taea kitea e koe puta noa i te tinana. Ko e maha ratou kīia ki rite "mariko" e macrophages tika ki te meka i whai wāhi ratou e i roto i te hanganga o te anga mo te nuinga o ngā hanganga o te tinana, e kore e tika te whakangaromanga o ngā āhuatanga kino.
4. pūtau Dendritic. ora ratou i roto i te epithelium me submucosal.
5. Splenocytes. Ko ratou i roto i oko toto sinusoidal o te tinana, ā, e whai wāhi i roto i te kite, me te whakangaromanga o tawhitotia o koutou pūtau toto. No miharo te kōateate huaina te urupa o mate pūtau toto whero.
6. macrophages Peritoneal. ora ratou i roto i te peritoneum.
7. Macrophages o nga taikiri. Hea ora ratou, he mea mārama i te taitara.

mutunga

uaua te reira i to tatou tinana. nohoia te reira i te momo o ngā pūtau whai hua, to tatou oraraa māmā e hanga. Ko ratou macrophages isklyucheniemi. Kia aroha mai, i ētahi wā e kore ratou e whai nui wheako ki te hanga i te mahi pūnaha ārai rite hiahiatia. A ka riro mate te tangata. Ko te painga nui o to tatou pūnaha ārai mate ko te mea ïa o ta te mea e taea ki te urutau ia.