Coagulation - he aha te mea te reira? Wetemunahia ana o coagulation toto: tohu, me te auau

"Coagulation - he aha te mea te reira?" - ka ui i roto i te ohorere, tūroro e kua tonoa ki te tango i te tātaritanga taua. I roto i te meka, e fehangahangai iwi noa ki te ako rite Varavara, te tikanga i roto i te faaineineraa no te pokanga fili. Tohu wā kaha me nga wahine hapu katoa. Analysis o te tukanga coagulation o mau ana i te tamaiti ko nga huatū.

I raro i te kupu kerekere teka ako toto. Whakaturia ai rerekē te tawhā ako i runga i te taiwhanga rānei. He tohu ka tohatoha te tātari. I roto i te take tuatahi te mea i whakaritea anake i roto i nei tika hono puta upoo- takahi tukanga. Coagulation tohatoha - momo o rangahau, i, i roto i te tua ki te kounga, me te rangahau ine me kohakore,. Ka taea te whakamahi i te reira ki te tāutu i ngā disorders mōtepe, ngā Thrombosis, hē o etahi āhuatanga upoo- me te rite. D.

Ko te huinga o tikanga e whakamahia ana ki te whiwhi i te hua, tei runga i te pikitia haumanu, te momo o te tātari māuiuitanga. Me kï reira e te tuhinga o te coagulation toto - ko te wero nui e kore hoki te tangata ke anake tenei, engari i ētahi wā ano hoki mo te tākuta. Tikanga, i roto i te tikanga ki te hanga i te tātaritanga tika, e te reira i te torutoru whakamātautau pai-whiriwhiri.

Ko te tukanga o te coagulation toto

Kia whai whakaaro tatou e founga te mahi pūnaha upoo-. I roto i te taahiraa matamua tohaina he kino matū hangarau ranei ki taiepa oko te thromboplastin - taonga motuhake triggering coagulation tauhohenga. Na, te faaitoitoraa o āhuatanga upoo- e wahi - pūmua motuhake e fa'a tonu i roto i te toto me te whakarato i te pae o te whara o te thrombus hanganga taiepa oko.

I tua atu, thrombin (he wāhanga tūturu o te pūnaha coagulation hua i prothrombin) whakahohetia te pūwētoto pūmua paruparu, faafariu reira ki te kaha puka pūtōtepe katinga te pūtake. Ko te āhuatanga o te toto, tae atu ki ngā platelets, "pohehe" i roto i te kupenga o te pūtōtepe. Ka rite ki te hua, tapahia platelets toto katinga me aki ki te hanga i te kati thrombus pakeke tūkino i te taiepa iaia. I roto i te rerekē, i te pūnaha toto coagulation i roto i te tinana te mahi ano hoki pūnaha protivosvertyvaniya. Fakataha tukua ratou ki a koe mau tonu toto i roto i te āhua tonu.

rangahau upoo- i roto i hapu

Ka rite ki kua whakahuatia, ia huatū, a i roto i ētahi wā, me te ake maha, ka coagulation wahine hapu. He aha te mea te reira a te aha ko reira e tika ana, e matau ana whaea expectant roa. Ko te meka ko e roto i te hapūtanga mahi pēpi o te pūnaha coagulation rite ake he katoa te. Ko te tukanga māori e pā ana ki te mea puta uteroplacental maimoatanga porohita toto tenei. Te whaea expectant pera faaineine mo te mate ka taea o te toto i roto i whanau ana.

Ki te tāutu i ngā āhuatanga o te upoo- toto, me te etahi pōauautanga o te hapūtanga hua coagulation. Haere tātari i mau hooraa wā rata e taea ui ki reira he ine i te tawhā noa hemostatic (wāhanga o te toto, me te toto oko, e taea ai mau tonu pāhekoheko te tapatahi o nga taiepa iaia, me mutu toto i roto i te take o te kino). Toto mo te rangahau tangohia i roto i te ata i runga i te puku kau i te rua.

Wetemunahia ana o coagulation toto

kia rāhuitia te hua ako o te tātari ki te mātanga. E kore e matau motuhake, e kore e te iwi e taea ki te kīa te tawhā coagulation me te aromatawai i to ratou tohu o te ine i te uara paerewa. Kia tamata tatou ki mahino te āhua kūware o te tukanga me te whakaahua i te tawhā taketake o te ako.

1. pūtaitoto

synthesized tēnei pūmua kei roto i te ate, tahuri i raro i te mana o etahi āhuatanga toto ki pūtōtepe. Me ngā tenei ahua te coagulation o toto. Pūnoa pūtaitoto - 2-4 g / l. Ki te nui haere te reira, upoo- nui haere te ware, a reira ko te mōrea o clots toto. Tikanga, puta tenei āhuatanga i mua i whanau, kakā, i muri i te pokanga, ki te mate me te mumura o te natura whakapeka (kohi, rewharewha), infarction myocardial me te patu (i te ra tuatahi), ki weranga, hypothyroidism, te whakawhānau kōrero me estrogens. kia pūwētoto heke e tika ana ki te tāoke, cirrhosis ranei kakā i roto i te puka kino, he hē o te huaora B12 C ranei te fariiraa i androgens steroids anabolic, te hinu ika, anticoagulants.

2. Hohea wā thromboplastin wāhanga (APTT)

tirohia Coagulation te wa i roto i nei, i muri i te hononga ki te wē konupūmā pūhaumāota me ētahi atu matū i hanga toto katinga. Ki te he i te iti rawa kia kotahi take coagulation i raro i te täkupu i 30-40 ōrau, aPTT huringa taumata. Ko te tere toharite, ko te 30-40 hēkona. kia whakanui i te wa ki te huaora K hē, mate ate. Ko te take mō te roa te aPTT me rite te putanga, ka taea e coagulation puhoi hei hemophilia.

3. Lupus anticoagulant

Kei tonu tenei tawhā te coagulation. He aha te mea tenei ahua? Ko wai e korero ki. Tenei IgC antibody me IgM, entailing he hua i roto i te aPTT. Tikanga, wahine hapu, kia kore e hua ratou. puta paturopi i roto i te take o mate autoimmune, gestosis. maha hua Pregnancy ki tenei māuiuitanga i materoto noa, mate fetal infarction o te ewe ranei.

4. Prothrombin

Ko te pūmua matatini e ko te kawainga o te thrombin (he pūmua e whakaihiihi ana te hanganga o clots toto). Tenei Ko tetahi o nga tohu tino nui o te coagulation. Prothrombin, me te whai wāhitanga o te huaora K synthesized te i roto i te ate. I muri te tātari i tenei uara, kia tautuhi te rata māuiuitanga gastrointestinal wahi me te ate.

5. Ko te wā prothrombin

Ko te wa i roto i nei te wē mā te tāpiri taua konupūmā pūhaumāota, i hanga thromboplastin me pūtōtepe katinga. Ua faaite tēnei ahua te i roto i te hēkona ka ko te tikanga rite ki te 11-15.

6. Prothrombin taupū (PTI)

maha tā Coagulation rite tenei kōwhiringa hei utu o te tetahi o mua. Tenei ōwehenga Ko te wa upoo- o wē tangata noa me te wē o te manawanui, ka whakaatuhia hei ōrau. I roto i te ōwehenga prothrombin noa kia rerekē i waenganui i 93-107 ōrau. E synthesized āhuatanga o tenei tawhā i roto i te pūtau ate, mate ate heke te ratou maha, kia IPT kēne ki etahi tohu mahi rite tawhā mo te āhua mahi o te tinana te whakatau.

Ki te nui haere PTI, na te nui haere upoo-, a reira ko te mōrea o te Thrombosis. Ka taea e tipu puta ka tango te whakawhānau waha, me te i roto i te marama whakamutunga o te mau ana i te tamaiti. Tuhinga o te taupū prothrombin tohu te ino o ngā āhuatanga toto coagulation. Ko te hanganga o ngā āhuatanga uaua prothrombin ti'aturi i runga i te huaora K, Heoi tona ngoikoretanga, malabsorption i roto i te piro (dysbacteriosis, enterocolitis) me kia uta e whakaiti IPT. Hoki, kia hua i roto i tango pota tiketike o ahipirini, Diuretics tenei.

7. wā Thrombin

Ko te wa i roto i nei te puta te pūwētoto ki pūtōtepe tenei. Ko tōna uara normative - 15-18 hēkona. Ko te hua i roto i tenei taupū kitea te i te kore congenital o pūtaitoto ranei i nui kino ate. Tuhinga o tawhā, arā, te whakaiti o te wā thrombin, tohu te aroaro o te paraprotein (immunoglobulin pūmua) he taikaha o pūwētoto ranei. Tikanga, te mana uara tohu i roto i fibrinolytics maimoatanga heparin ranei.

8. Antithrombin III

Ko reira he inhibitor o thrombin, he pūnaha pūmua anticoagulation. E ia he pānga depressing i runga i te tukanga coagulation. tohu Taumata whakaritea e here o thrombin i roto i te tauira whakamātautau (inhibition). uara Toharite o te antithrombin III - 71-115 ōrau. tautuhinga Whakaitinga ki te 50 ōrau o noa e faatupu te mōrea o te Thrombosis.

He nui rawa hoki nga wahine hapu tango anticoagulants te whakamāramatanga o tenei tohu. E whakamahia ana ēnei taero i roto i te whanautanga tamariki, ka nui haere upoo- toto te, a reira ko te ati o te hanganga o te iti hoki placental, hapūtanga whakamutunga.

9. D-dimer

Ko te tohu nui mo te tātaritanga o Thrombosis, e ngā coagulation tenei. E whakaatu ana tēnei tawhā? heheu e ia nga tukanga o te Thrombosis me fibrinolysis. Tikanga, D-dimer he iti iho i te 248 ng / ml. Kei te tīmata i te tohu taumata ki te tupu i roto i nga tīmatanga o te hapūtanga. Hei waiho te uara tawhā kia nui ake i te tuatahi e toru ki te wha nga wa. Kei te whakaaro te reira i te täkupu. He auau teitei i roto i nga wahine ki te akoranga uaua o te hapūtanga (preeclampsia), me te hunga e mamae i mate tākihi, mate huka.

10. platelets

Kei te whai wāhi te reira i roto i te whakarato platelets hemostasis. E hanga e ratou i roto i te hinu wheua wheua. uara normative - 150-400 mano / ml. I roto i ētahi wā, i roto i nga wahine hauora kia wheako i te hekenga i roto i te mōtepe tatau ki 130 mano. / L. He nui heke i roto i ngā huānga raraunga toto i huaina "thrombocytopenia" me puta rite ki te hua o te whakaiti i te hanganga o platelets, te whakanui ake i to ratou kohi whakangaromanga ranei. Ki te iti rawa tōtika heke mōtepe hanganga. I hoki, ka e kia kōrero i raro, kua whakaahuatia reira piki pūtau toto āhua.

11. hoki

Ngā pāhekoheko o platelets, āhuatanga coagulation me te tukanga fibrinolysis whakarato te pauna i waenganui i ngā pūnaha coagulation me anticoagulation. Ki te mea ka mamae tetahi o enei hononga disorders i roto i te hapū e taea meinga etahi pōauautanga nui. Ko te kino te nuinga o ratou tohatohaina te coagulation intravascular. whakawhanake te reira i rite ki te hua o te faaitoitoraa o te pūnaha fibrinolytic me te pūnaha coagulation. I roto i nga wahine hapu, kia ki nga take o hoki Embolism waikahu, wehe taimi halá, o te ewe, endometritis.

12. Ko te syndrome antiphospholipid (ApS)

Ko reira he matatini o tohu e tohu Thrombosis (venous me te matua). Women ki ApS i te mōrearea nui o materoto me te takanga o te materoto noa, no te mea i roto i tenei take i te hua i roto i te maha o oko o te ewe ohorere te me te whakawhanake i iti hoki fetoplacental. Hei tātari syndrome anti-phospholipid, nui haere thrombogenesis i tua, kitea ano paturopi ki te kiriuhi anga waho (phospholipids).

I roto i te mutunga

e kore e ngaio coagulation whakaaro tohu. Ka rite ki tuhia i runga ake, te kōwhiringa o ngā tawhā motuhake mo te ako tei runga i ngā āhuatanga. ka hei Hua o te tātari e wātea ana i muri i te ra i muri i hoatu toto.