Ko te tarukino "Celebrex": arotake, analogs, tohutohu mo te whakamahi, utu

Ko te hinganga o te tuarā, te mamae nui i roto i te hononga, me mahi huringa kiko tūhonohono i runga i te whakamārama o te mumura - kāore, ko enei mate te tino noa i roto i to tatou wa. I pā tenei āhua o ngā take āhua, te kore o te mahi tinana noa, āhuatanga ira. I tua atu te mamae kino e mamae iwi i roto i tenei huru ki, ma'i ahei o whakangaro te rauropi katoa, liliu matū toto, me te pa ana te mahi noa o whekau.

Ko reira he mea nui ki te aroturuki i te hauora me te wa ki te hamani i te mate. Ko tētahi o nga taero whai hua te nuinga, e no ki te rōpū o taero kore-steroidal i huaina medicament "Celebrex". Reviews o tākuta whakau tona tōtika i roto i rite ki te aho ano o taero anti-inflammatory.

Ko te pānga matua o te tarukino

He painga o te tarukino kia huaina ai tona kaha ki te tautāwhi i te mahi tukanga inflammatory i ngā wāhanga rerekē o te mate. Kia i roto i te toto, e taea ki te tautāwhi i tukanga TSOG2 e tika ana ki te awhina o mumura te tarukino ko. "Celebrex" te raau taero e te taonga analgesic mahi kaha antipyretic. Na reira, i te reira faaore kore anake te aronga mumura, engari ano maitai tango ara mamae nui, te whakaiti kirika.

Ko te painga o tenei hua ngā ona pānga iti i runga i te platelets, e ko, te tarukino e kore meinga raruraru ki upoo- toto. A, no te riro koe i te kaihoko kore-steroidal e kahore he ritenga o te puku me paru, heke te mōrea o keha me tūroro gastritis.

Na reira, kei te whakamahia te "Celebrex" pire nui atu whānui atu i te tahi atu raau taero NSAID, "naproxen", "ahipirini", "ibuprofen".

aronga

"Celebrex" capsules i te kaha ki te whakaiti i te pakeke o te mamae tahi, pakeke faaore akakoromaki ratou ki ngawhatanga nui. taea taua te rongo ki te hamani tūroro pāngia ki kaikōiwi, osteoarthritis. Pānga o te raau taero tae ko te pānga mōrahi 24-48 haora i muri i te horopeta tuatahi. tōtika Dysmenorrhea raau faaore te mamae, ara te whakapeka tino. Ano, Kei te tōtika whakamahia ai mo te tanga o te mamae i muri i te pokanga (maxillo-kanohi me te pokanga orthopedic).

Tūroro ki ankylosing spondylitis tarukino "Celebrex" mawehe nga tukanga pathological me whakapiki kaha o te tinana ki te mahi. A, no te mātakitaki i te akiaki o te utuafare, te whakamahi polyposis adenomatous o te tarukino arahina ki te whakaiti nui i roto i te tupu o polyps i roto i te kopirua me duodenum: whakaiti ratou tokomaha, me te rahi. titau Doctors rawaka pota o rongoā me te ū ki regimens maimoatanga e taea e te whakatutuki hua pai ki te whakamahi o "Celebrex" tarukino. whakaatu Mua pānga taha iti ia tango i tēnei rongoā.

Ko te āhua me te hanganga o te tarukino

Tino inhibitor whiriwhiri ko te capsule gelatin tata ma ma ranei, e kore e ratou mārama me kua tohua ki te takai puru tapanga "7767" i runga i tetahi taha, me te "100" me "200" i runga i te tahi atu. tirotiro capsule: granulated tae ma.

Ko te hanganga o te tarukino ngā: celecoxib (taketake whakauru kaha), reihuka, povidone K30, konutai lauryl pūkawa, stearate konupora, te konutai croscarmellose. hanga te anga te o Titanium hauhā, me gelatin kai. Ki te whakaritea whakahaere e tika ana o te tarukino werohanga intramuscularly "Celebrex". tukua tenei momo o te rongoā i roto i te puka o te otinga mō te werohanga o 2.2 ml ampoules - taketake taonga celecoxib.

Pharmacokinetics

I pai te whenumi te tarukino ki te toto i roto i te āhua nohopuku me tae te mahi mōrahi i muri e pā ana ki 2-3 haora. Heoi, te whakamahi o te tikanga tahi ki te fatty kai kia whakaroa tona whakaeminga mō te 1-2 haora. Na reira he mea tika ki te kōrero i te tākuta e pā ana ki te wa o tango te rongoā.

Kia i roto i te bloodstream, e kore e nga matū kaha herea ki ngā pūtau toto whero, engari e kore e te huarahi pā te paetae o te kukū e hiahiatia ana o te raau taero i roto i te tinana. Drug metabolized i roto i te ate i te hāora me te glucuronidation e whai wāhi mai CYP2C9 whākōkī. tikanga Huaputa ki mimi me feces i te puka o metabolites ohie, a ka noho tonu% 3 anake o te taonga kaha tonu.

Drug "Celebrex", analogues o nei he rite i roto i te hanganga, i kitea te tikanga, meinga iti kino ki te hauora, e tika ana ki tona kaha ki te kia whenumi nui taea, me te tata rawa whakakorea i te tinana. Ki te taimaha tinana iti kitea he kukū teitei o tarukino i te toto, a ka rite tenei āhuatanga e neke atu i roto i nga wahine. e kore e mohiotia te reira he aha, engari ano hoki i roto i te iwi mangumangu kitea te taua akiaki. Na reira, i enei rōpū o tūroro whakaritea he horopeta raro o rongoā i te timatanga o te therapy.

Tuhinga

Ka rite ki te kore-steroidal anti-inflammatory māngai mo te tarukino maimoatanga symptomatic whakaritea "Celebrex". Tuhinga mō te whakamahi:

• kaikōiwi;
• osteoarthritis;
• spondylitis;
• algomenorrhea;
• mamae whakapeka (wā pou-operative, hoki te mamae, mate musculoskeletal);
• whakamahia i roto i te maimoatanga o adenamotoznogo polyposis.

Me kï reira e taea tika maimoatanga tautapa anake te tākuta i runga i te pūtake o te rangahau.

Methods o whakahaere o te tarukino

Ka mau i te tarukino me kia roto, ahakoa o te kai. e kore e papa Chewable kia, e hiahia ana koe ki te inu i te wai mania. Me kï reira e taea pōauautanga Cardiovascular puta ki whakahaere ma'i o te tarukino. Na reira, tākuta whakahau "Celebrex" he akoranga poto o te maimoatanga. tohunga te āheinga whakaū e kore e nui ake te horopeta mōrahi mō te maimoatanga wā roa-400 mg ia ra!

• Maimoatanga o osteoarthritis - rawaka horopeta ko 200 mg ia ra. Chance o te horopeta kotahi ranei ritua ki e rua (i wā auau).
• kaikōiwi - horopeta tūmanakohia o 100 200 ranei mg ki 2 nga wa ia ra. A, no te nga puka tino kino - ki runga ki te 400 mg rua he ra.
• spondylitis Ankylosing - 200 mg ia ra, mo te 1 ranei 2 werohanga wehea. I roto i te ngarahu pai o te tākuta kia nui haere te horopeta ki mau āta
• Dysmenorrhea me te mamae kaha - haamata therapy ki 400 mg ia ra, a tapiritia tetahi 200 mg i te ra tuatahi o te therapy, ki te tika. I roto i nga ra e whai ake nei, me tango e koe 200 mg rua he ra.

whakaritea roanga o te maimoatanga e te rata haere.

Contraindications ki te whakamahi o te raau taero

I tua atu ki taea tauhohe mate pāwera ki kaipōti o te raau taero, i reira he here i raro i nei e rāhuitia i te whakamahi i te tarukino "Celebrex":

1. huangō arahau, urticaria, pāwera ki ētahi atu NSAIDs.
2. Ko te wā postoperative i muri i aortkoronarnogo karo.
3. whewhe keté (exacerbation).
4. toto GI.
5. mate whēkau inflammatory.
6. rahunga Heart.
7. Pākaha iti hoki ate.
8. iti hoki tākihi.
9. Pregnancy me te hohipera.
10. Ehara i tūtohutia hoki te whakamahi i raro i 18.
11. Hypersensitivity ki nga kaipōti o te tarukino me sulfonamides.

Whakatūpatotanga kia whakamahi i te tarukino ki pupuri wai i roto i te tinana, mate o te pūnaha Cardiovascular, mate huka.

pānga taha

Ahakoa te mananga tiketike o te raau taero, auroa hē ranei aratau fariiraa me te inenga e taea e ngā pānga taha o te tarukino "Celebrex". whakaatu Mua te tino noa (auau) tohu pērā i:

• mate pāwera tae atu hikaka, urticaria, pruritus.
• Flatulence, dyspepsia, edema, ohoroa.
• Mare, Rhinitis, tauhohenga rewharewha-rite me te mate wahi romahā.
• mate mimi.

He nui iti i reira he nui haere manukanuka, anemia, tinnitus, flushes, arrhythmia, takawhita matua. I tuhia ētahi tūroro ulceration o te wahi kūnatu, edema angionevropatichesky, te hanganga o te bullae i runga i te kiri, exacerbation o pancreatitis tona whanaketanga ranei, te whakama. Ka taea e anake enei tohu katoa puta ina he poto (ki runga, ki te 12 wiki, e kore rawa 800 mg ia horopeta) he akoranga o te maimoatanga. Otiia i roto i te take o te maimoatanga wā roa-(ki runga, ki te 3 tau) e kitea:

• Common: inoino o te heamana, takawhita, mate o nga taringa, angina, infarction myocardial, whakapairuaki, dysphagia, prostatitis, nui haere creatinine.
• Nui atu te utu: arrhythmia, angina, patunga rere pūroto, atherosclerosis, whakararuraru moe, toto tara, tuwhenua o te mangai, dysmenorrhea, hua i roto i te pūtoto, heke i roto i te hematocrit.

Ko te pāhekoheko o te tarukino me te tahi atu raau taero

Ko te medicament kaha biotransformed whai wāhi P450 2C9 (cytochrome). reira i te mea taea pāhekoheko tika o te tarukino me ētahi atu āpiha:

1. whakamahi te rere o taero "fafati" faarahi te mōrea o te toto mate.
2. Te faaineineraa "Ketanazol" me "Fluconazole" ake i te kukū o kaha taonga celecoxib tata rererua.
3. Te fariiraa blockers inhibitors ACE ranei NSAIDs angiotenzita kia tino whakaiti ratou antigipertinzivny pānga
4. hua huinga kei roto lithium, taea tino whakanui i te reira i te taumata toto.
5. Kei te riria te reira ki te whakamahi i te wā kotahi i te tarukino "Celebrex" analogs kei roto celecoxib, te tahi atu NSAIDs!

analogues tarukino

E tano ia tapao e kore "Celebrex" utu tarukino rawa nui, ko tona utu i runga i toharite i 400 ki 450 moni. 10 capsules (100 mg inenga). Heoi, he tino utu mo te therapy wā roa-o te manawanui taua maimoatanga. I roto i tenei take, te whakaae o te tākuta, whakarite māngai kei roto celecoxib. Hoki tarukino "Celebrex" analogues o te whai ake:

• tarukino "Ranselak";
• tarukino "Revmoksib";
• papa "Flogoksib";
• capsule "Artoksib".

Kei roto ēnei analogs te taonga kaha taua, me te whai i te pānga haumanu nui ōrite i roto i te maimoatanga o mate. Kia mahara e hoki whakaritea he horopeta tika o te orotahi anake i te rata haere. I roto i tenei take whakaaro te tākuta rerekē ngaahi tokoni hanganga i roto i analogs, i roto ratou ngā tāpiritanga rite whakaritea ki tarukino "Celebrex". Ako arotake te tākuta whakaaro te taea o te tauhohenga pāwera i te manawanui ki nga excipients o rongoā rerekē kotahi rōpū.