"Formetin": tohutohu mō te whakamahi, tūturu

I tēnei wā ka kitea e matou atu iwi ki te mate huka, me te pōauautanga o te momo mōmona. He maha raau taero e wātea ana mo te maimoatanga o enei ma'i. Ko tētahi o ratou ko te rongoa "Formetin". Ka kia faataa ona āhuatanga salient i roto i tenei tuhinga.

kāwai ho'oraa

"Formetin" tohutohu mō te whakamahi whakaaturia nei i roto i tenei tuhinga, ko te rōpū tarukino hypoglycemic biguanide.

Whakaahuatanga o te puka hanganga me te tuku

I roto i tetahi o ona papa:

tarukino wātea "Formetin" i roto i te paku 100, 60 ranei 30 papa.
Tei tae White papa me inenga puka i runga i te rauemi turanga. I 500 mg ploskotsilindricheskoy to ratou he āhua porohita ki te tohu, me te chamfered. Hoki te inenga o 1000 mg 850 mg ranei kua "Formetin". Ko te papa i roto i tenei take, koropuku, me te porotītaha. Ko ratou mōrearea-iu kotahi.

pharmacodynamics

Metformin ( "Formetin") pōturi gluconeogenesis e rerengia ana i roto i te ate, me te kupu i reira ko te hekenga i roto i te glycogen toa reira. whai wāhi ana tēnei taputapu ki te uaua o absorption i te kūhuka intestinal, whakarei te tango o nga taumata huka toto o te pūnaha. faarahi tenei te whakautu o te kopa ki te taiāki huka i waho e pā i te hanga o ona wahi endocrine o te repe taiaki B-pūtau, bypassing tauhohenga hypoglycemic, mai i kore te reira whakahohe hanga o mea taonga.

Drug "Formetin" arotake e kōrero e pā ana ki tona whai huatanga, te whakaiti i te nui o toto i roto i te "kino" cholesterol me pāhare. Ko te ihirangi o lipoproteins kiato tiketike faarahi tenei ki 20-30%. Ki te tauturu te memeha noa o te kai tarukino "Formetin" tohutohu mō te whakamahi whakaahuatia nei i roto i tenei tuhinga ki te whakaiti me te / ranei ū o te manawanui taimaha. tupu tenei e tika ana ki te hāora o te kūhuka i te hāora-free, me te whakaiti i hiahia. te mea kua poutoa ano e reira kiko tukanga whakahohe plasminogen mā te mahi i runga i tona inhibitor, ai puta te pānga hemostatic.

Pharmacokinetics

tīmata whakawhenumi metformin i roto i te wahi gastrointestinal. Ko te rahinga mōrahi o te taonga i roto i te toto, ko e pā ana ki 2.5 haora i muri i te tono i te tere o te absorption wae horopeta - 50-60%. pānga momi kounga o tarukino i roto i te tinana i te hononga i waenganui i te taonga kaha me te pūmua i roto i te wē. I roto i te papa "Formetina" kahore hononga ki pūmua wē. korero te reira e pā ana ki tona whai huatanga. Mai te iti te take here, kei te pai whenumi te rongoā. Waipara Ko te tākihi, ate, i roto i te uaua kikokiko, i roto i te repe salivary. I roto i te tinana, e noho tonu metformin. Ia muri excreted e nga whatukuhu. Na reira, i roto i te take o te ofatiraa o ratou mahi kitea te whakaeminga. Koiora hawhe-ora ko 1.5-4.5 haora.

iku'anga

Medicine "Formetin" te whakamahia mo te maimoatanga o etahi ngā kāwai o mate. Ara, i roto i te aroaro o te momo II mate huka, me ngā take mōmona ki uaua ka kore e tauturu i te kai ki te pupuri i ngā taumata huka toto noa, ara i roto i te huinga ki te sulfonylurea. whai hua hoki ko te "Formetin" mo te ngaronga taimaha.

Me pēhea te ki te tango?

Ko te horopeta o te tākuta tikanga e tīpakotia, e hāngai ana i runga i te nui o te kūhuka i roto i te toto. he tika whakahaere Oral ki te faaohipa i muri i te kai, inu ki te nui o te wai, me te whaki i te machining papa. Ka rite ki kua whakahuatia i runga ake, whakaritea te inenga i runga i te ihirangi o te kūhuka i roto i te toto rānei. E haamata te reira ki te nui iti rawa - 0.5 g 0.85 g ia ra ranei. E rua nga ra i muri i tīmata maimoatanga ki tenei raau i te ihirangi on o metformin i roto i te toto, kua. Te kōwhiri, āta whakapiki i te horopeta noa te uara mōrahi. Ko reira ōrite ki te 3 karamu.

Mai i te kaumātua maha kitea te whanaketanga o te acidosis lactic, hoki ratou kua heke hoki te taumata o te horopeta mōrahi rā o nui 1 go o te raau taero i roto i te ofatiraa o te ka pākia e, i roto i te tikanga ki te ārai i te tauhohenga pāwera, e faaite ake i roto i te puka o rashes kiri, a era atu meatanga kino taea, ka e kia tohua i raro.

contraindications

I roto i tenei whakaaro, i reira e maha onäianei. Drug "Formetin" tohutohu mō te whakamahi whakaaturia nei i roto i tenei kuputuhi, contraindicated te i te aroaro o:

• ketoacidosis mate huka, precoma, pōroa.
• Pākaha taumahinga tākihi waimaero.
• kore cardiac me romahā.
• wāhanga whakapeka o infarction myocardial.
• Maroketanga.
• waipiro ma'i me ētahi atu tikanga e kia whai wāhi ki te whakakitenga o te whakawhanake acidosis lactic.
• patunga whakapeka.
• Pregnancy me te ū.
• Hypersensitivity ki tenei srudstvu.
• tafa Major ranei whara, ka whakaritea taiāki te.
• Taumaha mate hopuhopu.
• disorders Taumahi o te ate.
• paihana waipiro whakapeka.
• acidosis lactic (tae atu hītori).
• kai Hypocaloric (iti iho i te 1000 kcal. Per ra).
• Adioizotopnyh ranei rangahau radiographic, te whakahaere o te momo taonga konutawa.

e kore te tūtohu hoki te reira ki te whakamahi i te tarukino "Formetin" tangata i runga i ono tekau tau, e mahi ana mahi i te pae tino ohie. Mai i roto i tenei take, kua ratou he kaha ake te tūpono o te whakawhanake acidosis lactic.

pānga taha

Ko te takanga o taua tohu kino rite "konganuku" reka i roto i te mangai, ruaki, whakapairuaki, korere, flatulence, kore o te hiahia titau korenga atu o te whakamahi o te maimoatanga me te tuku tonu ki te mātanga. whakamahi wā-roa o te tarukino ai te ngangau oti paipa o te horomanga o te huaora B _12, e arata'i ki te haaputuputuraa i roto i te tinana o te muri, meinga hē huaora ranei. I roto i te wā onge, te whakawhanake whakamuri - megaloblastic te anemia _12-kau. Ki te hē whakahaere horopeta e suka taea. kia wheako hoki e koe te mate pāwera pērā i ponana kiri. Na reira, i te tarukino "Formetin" arotake i runga i tona tika i roto i te whakamahi o rerekē, kia whakaritea anake i te rata haere.

Ara

He āhuatanga nui tautuhi paearu pupuri taketake taonga "Formetina" i roto i te tinana, me te putanga o tenei.

Kia kore ai haaputuputuraa o acidosis lactic me te ārai o te metformin, he mea e tika ana ki te aroturuki i te tohu o te tākihi mahi me mo whakamātautau ki te whakatau i te ihirangi o te waikawa lactic i roto i te tinana i te iti rawa 2 nga wa ia tau. Ano, ki te whai koe i kia retested mamae i roto i te uaua.

Ko te pānga o te mea tarukino i runga i te kaha ki te pei ngā tikanga, me te peia waka

I roto i tenei take, kia rite ki reira e etahi onäianei. Pānga "kaha Formetina 'ki te mahi mīhini me te waka e wahi anake, ki te whakamahia i roto i te taha ki te taero e pa i te tukanga mahi e rapu te tere o ngā urupare, me nui haere kukū. He mea nui ki te mohio.

Taupānga o te hapū me te whāngai ū

Te faaineineraa "Formetin", tohutohu mo te whakamahi o nei whakaahuatia te nei, he pānga i runga i te te kukune kāwai «B» e FDA. I roto i te hapū e riro i tenei moni. Heoi, ka taea e tona whakamahi e anake i roto i etahi wā. Ara - ka e nui ngā hua e tūmanakohia ana i tenei therapy te wātea o te tūpono ki te kukune. rangahau motuhake, me te take i runga i te whakamahi o te taputapu pērā i te tarukino "Formetin" i whakahaere i roto i te wā o te hapūtanga. I te wa o te maimoatanga e mutu whāngai ū. I roto i tetahi take, e hiahia ana koe ki te kōrero i te rata tohu.

taunekeneke tarukino

faarahi Metformin te taumata o te huka toto. Ko te tino kitea ki te fariiraa tukutahi o te kore-steroidal taero anti-inflammatory, pārōnaki sulfonylurea me clofibrate, inhibitors monoamine oxidase, acarbose, taiāki, oxytetracycline, cyclophosphamide, inhibitors o angiotensin tahuri blockers paru me te momo tenei.

A, no te tono tahi me taero endocrine (te whakawhānau-waha, corticosteroids, sympathomimetics epinephrine, hormones thyroid repe, glucagon, thiazide me "koropiko" Diuretics, pärönaki phenothiazine, pärönaki waikawa nicotinic) kia metformin tukanga braking hypoglycemic.

Ki te huinga o te taputapu pērā i te tarukino "Formetin" ki "Tsimidinom" "nifedipine" tipu mōrea o acidosis lactic, metformin hëoi te excretion i te tinana. Taua kitea i roto i te mahi o nga hua waipiro, i roto i te Vol. H. I roto i te hanganga o ngā rongoā.

āpiha Cationic (quinidine, amiloride, digoxin, procainamide, rehunanu, quinine, vancomycin, ranitidine, triamterene) i hanga i roto i te tubules, tata'u nei te pūnaha ikiiki me te maimoatanga wā roa-kia whakapiki ake i te taumata o te kukū tarukino ki te 60%.

tuwhena rawa

Tuwhena rawa "Formetinom" kite ina tango 0.85 karamu ia ra, me te whakapataritari acidosis lactic. Ano, he ihirangi tiketike o te metformin tika ki te kore tākihi.

tohu wawe o te acidosis lactic ko te ngoikore o te tinana katoa, bloating, iti pāmahana tinana, mamae i roto i te kopu, me uaua, te pēhanga toto raro, bradyarrhythmia pūpū. I roto i ētahi wā, i reira he faaiteraa auau o disorders romahā, whanoke, a, rite te putanga, i reira ko te whanaketanga o te pōroa.

I te iti o ngā tohu o te tuwhena rawa kia mutu te whakamahi i te tarukino, me te kōrero i te tākuta ki te whakaū i te tātaritanga o te acidosis lactic. Hoki tango o te taonga kaha o te kaihoko, me te waikawa lactic i te kaiao e tātari toto whakarara ki maimoatanga symptomatic.

"Formetin": ritenga

He he rota o ngā rauemi o tenei momo. Analogues "Formetina" protrude formulations kei roto i roto i tona hanganga rite te wāhanga matua o te metformin hydrochloride. Ko tētahi tauira ko te tarukino o ngā Russian, "Vero Metformin," "Gliformin", "metformin", "Metformin-Richter", me tāwāhi - "Glucophage", "Glucophage" me "Glyukofazh Long" (France), "Lanzherin "(Horowākia)" Metfogamma "ki rerekē toketaá o taonga kaha o 0,100, 0.500 me 0,850 g (Germany).

Here me ngā

I roto i tenei whakaaro, i reira e etahi tikanga. Te faaineineraa "Formetin" ko te puai, na te tukua reira anake i te whakahaunga, me te titau rokiroki i te pāmahana rūma, i roto i te taea o ngā tamariki, me te wahi rā. Shelf ora ai - 2 tau.

utu o

whakaturia te utu toharite mō te tarukino "Formetin" kei runga i te inenga i 59 moni rānei. 0.5 go o te namunamu, 133 moni. o 0.85 g, me te 232 moni. i runga i 1 tau

mutunga

te mua katoa ngā he rota o te kōrero whai hua. I muri te pānui i tēnei tuhinga, ka taea ki te kitea he whakahoki ki te pātai o te pehea, ki te tango 'Formetin "me aha kua reira āhuatanga katoa.