Heparins iti taimaha rāpoi: taero, tohu hoki te whakamahi

e kore he Therapy o ngā Thrombosis me thromboembolic kahore anticoagulants, e ngā iti heparins taimaha rāpoi. Enei matū i roto i te hanganga o ngā rongoā te whakarereke upoo- toto, reira whakaora patency.

Ngā momo o anticoagulants hāngai

Whakaaro i te huarahi o te pānga o pūhui antithrombotic kia tuhia ai e he ratou mahi hāngai, me te autaki. Ko te rōpū tuatahi tino whakamahia nuitia o matū.

E wehea Anticoagulants mana tika i runga i te hanganga ki iti heparins taimaha rāpoi, me te unfractionated. Ka taea hoki e ratou inhibitor thrombin tika, he reira pehea, mo te tauira, hirudin.

Iti Āhuahira heparins taimaha rāpoi

Ratou pūhui fractionated rerekē i huaina nei toharite rāpoi taimaha awhe i 4000 ki te 6000 daltons. E pā ana ratou mahi ki te inhibition autaki o te hanganga me te mahi o te thrombin whākōkī. puai taua te heparin pānga i runga i te take toto coagulation Xa. Ko te hua ko te anticoagulant me pānga antithrombotic.

E whiwhi iti heparins taimaha rāpoi i matū unfractionated taratahi i epithelium intestinal poaka, i roto i te tukanga o te depolymerization matū enzymatic ranei. Ka rite ki poroa te hua o tenei tauhohenga hukarau mekameka e tetahi-toru o tona roa taketake, e āwhina ki te whakaiti i te rāpoi ngota anticoagulant.

He ngā iti heparins taimaha rāpoi, me hāngai tenei whakarōpū i runga i nga tikanga o te whiwhi pūhui te tote-kei roto.

issuance

Ratou formulations he rongoā injectable mō te whakahaere subcutaneous rō-uaua ranei. Kei te nuinga o Kikī ratou i roto i ampules pāhorehore tuku ranei.

e kore e iti heparins taimaha rāpoi whakaputaina i roto i te papa.

e kore te rongoā Intramuscularly whakamahia.

Whakaahuatanga "Gemapaksan" tarukino

E pā ana te reira ki raau taero ki ngā pānga anticoagulant tika. Ko te whakauru kaha i roto i te puka o te enoxaparin konutai tote, whakaaro nei ko te pārōnaki o heparin. whakarato ana tēnei whakarerekētanga he adsorption tiketike, ka whakahaere subcutaneously me takitahi tūtohutanga iti.

Kei te whakaputaina te reira e te kamupene Italian "Italfarmako SpA" rite te otinga mārama, te huitahi marama-kōwhai ranei mo te werohanga tākai i roto i pāhorehore o 0.2, 0.4 0.6 ranei ml.

enoxaparin konutai inenga e ki 2000 Iu ki 20 mg; 4000 Iu ki 40 mg me 6000 mg o 60 Iu. rewa te whakauru kaha i roto i te wai i te werohanga tarukino.
faaite Enoxaparin konutai i roto i te inenga o te 100 Iu ia 1 mg o pānga inhibitory tiketike i runga i te take toto coagulation Xa me antithrombin pānga iti i te horopeta 28 Iu ia 1 mg.

E kore e te whakamahi o nohanga tarukino whakaora i roto i te tini o nga mate arahi ki te hua i roto i te roanga o te mate toto.

e kore e prophylactic inenga konutai enoksaparinovaya e whakarereketia te wa thromboplastin wāhanga whakahohe, e kore e ofati i te clumping mōtepe me ratou tukanga hononga ki te rāpoi ngota pūtaitoto.

heparins iti taimaha rāpoi i roto i te kukū tarukino nui (6000 Iu i 0.6 ml) e whakamahia:

• mo te therapy o Thrombosis i nga uaua o te rire;
• te hanga i angina iu me te myocardial auheke huru uaua infarcted i roto i ngā ki te waikawa ahipirini;
• mo te ārai o te coagulation nui haere hoki te roanga o te tukanga tātari toto.

Kupu Whakataki subcutaneous dosing otinga 2000 me 4000 Iu o 0.2 me 0.4 ml, aua, Kei te whakamahia ki te ārai i Thrombosis me te pūnaha huru thromboembolic venous:

• i roto i orthopedic huru ngā mahi hāparapara;
• moenga mō ngā tūroro ki iti hoki romahā ma'i wae pūnaha cardiac 3 me te momo 4 ranei;
• whakapeka mate hopuhopu rūmātiki ranei, te wahi i reira he he take mōrearea mō clots toto;
• tūroro kaumātua;
• ki te taikaha waipara ngako;
• ka taiki therapy.

whakamahia te raau te subcutaneously ki te taiepa puku, i roto i tona posterior me rohe anterolateral.

contraindicated rongoā te mo te thrombocytopenia, toto, disorders upoo-, mate ulcerative o te membrane mucous o te puku me te duodenum, subacute endocarditis kitakita, mate huka, mate huka, te tūtohutanga tiketike, me te hapū.

"Gemapaksan" Medicine: utu

Ko te utu o te werohia kei roto 2000 Iu pūwero i roto i te 0.2 mL o ono nga wahi o 955 moni.

Hoki atu inenga tarukino "awhe utu Gemapaksan 'i 1,500 moni ia mōkihi ki ono pāhorehore.

Whakaahuatanga "Clexane" tarukino

E pā ana te reira ki te taua tikanga i runga i te pūtake o te enoxaparin konutai. I whakaputahia e te kamupene French "Sanofi Aventis" hei otinga mārama injectable e taea e taekore ranei ki kauruku paku kōwhai.

He inenga "Clexane" faaineineraa o 10000, 8000, 6000, 4000 me te 2000 Iu o enoxaparin konutai ki 1.0; 0.8; 0.6; 0.4; 0.2 ml o te raau taero wai, aua. Te whakauru mātātoa i roto i te otinga, ko te 1 mg 1,000 Iu.

E hangaia iti heparins taimaha rāpoi i roto i pāhorehore karaihe, e kia i roto i te mōkihi 2 ranei 10 nga wahi.

Drug "Clexane" i runga i HIV ārai thrombotic me disorders thromboembolic i roto i te uaua i roto i te wawaotanga hāparapara e pā ana ki orthopedics, me tātari toto.

I whakahaere te otinga subcutaneously i whakakorenga o āhua thrombotic venous i roto i te pukapuka hohonu, me ki te uaua.

Drug whāki i angina āhua iu o te uaua auheke, me te myocardial myocardial i roto i te taha ki te papa "ahipirini".

"Clexane" Medicine: utu

Ko te utu o te werohia kei roto 2000 Iu 0.2 mL ia pūwero ko 175 moni.

Ko tētahi wae horopeta o 4,000 Iu ki 0.4 ml o te RUB 280 e whai ki te utu mo te 6,000 Iu ia 0.6 ml - 440 moni 8000 Iu ia 0.8 ml - 495 moni.

I roto i te faaineineraa "Clexane" utu ia wae o 10 nga wahi ki te horopeta o te 20 mg, 40 mg me 80 mg ko 1685, 2750, 4000 moni.

Whakaahuatanga "Fragmin" tarukino

Ko te wāhanga kaha o te tarukino ko te pärönaki o heparin taonga kanohi dalteparin konutai. Kei te whiwhi te reira na roto i te depolymerization i te mahi o te waikawa Sinks , aru i te purenga te whakamahi i utu katote tūrara. Kei Dalteparinovaya konutai tote mekameka hukarau i raro ki te sulphation, ki te taimaha rāpoi toharite o e rima mano daltons.

Ngaahi houalotú protrude werohanga wai me te konutai pūhaumāota tote. whakaahua ana Beletita medicament "Fragmin" ā rite te otinga mō te werohia subcutaneous me te whakahaere rō-uaua i roto i te puka wai kauruku taekore kowhai ranei mārama.

Ko tōna tuku i roto i pāhorehore karaihe monodose o 2500 Iu ia 0.2 ml; 5000 Iu ia 0.2 ml; 7500 Iu ia 0.3 ml; 10,000 Iu i 1.0 ml; 12,500 Iu i 0.5 ml; 15,000 Iu ia 0.6 ml; 18,000 Iu ia 0,72 ml.

E taunaki ana Drug "Fragmin" ā te whakamahi i te mehua ārai mo te mana o te toto upoo- tikanga i roto i te tātari toto me te haemofiltration ngā mahi e hāngai ana ki te maimoatanga o te hēnga o ōna whatukuhu, ki te ārai i te hanganga o clots i roto i te pokanga.

whakahaerea ana te medicament te ki te whakakore i te pāpaka thromboembolic tūroro ro'i.

Rongoā whāki i angina, iu me te infarct kāwanatanga auheke myocardial o nga uaua, symptomatic thromboembolism venous.

Whakaahuatanga o te tarukino "Anfibra"

Kei te tuku tōna iti heparins taimaha rāpoi ki te kamupene Russian OJSC "Veropharm". He he he otinga mārama mō te werohanga, e kia kauruku taekore kowhai ranei.

Waiwai tikanga he konutai enoxaparin tote, e kia roto ai 2000 Iu i 0.2 ml; 4000 Iu ia 0.4 ml; 6000 Iu ia 0.6 ml; 8000 Iu ia 0.8 ml; 10,000 Iu i roto i 1.0 ml. whakamahia te wai māturu te rite whakarewa.

prepacked te reira i roto i ampules pāhorehore o 1ml ranei, e e 2, e Kikī 5, a 10 nga wahi i roto i mōkihi o te pepa.

e tūtohu Drug "Anfibra" ako mō te ārai o te huru thromboembolic ina mahi whawhe me te tātari toto i roto i te maimoatanga o te hanganga katinga i roto i te oko hohonu-takoto.

Rongoā penei te āhua iu o angina me kāwanatanga uaua infarct cardiac i roto i nei kahore niho Q i runga i te hiko-.

Whakaahuatanga o "Fraksiparin"

heparins e taimaha rāpoi iti no konupūmā nadroparin, i whiwhi nei te i roto i te tukanga depolymerization. Ko tōna rāpoi ngota he glycosaminoglycans, te taimaha rāpoi toharite o te mea rite ki te 4.300 Daltons.

Kei faaineineraa "Fraksiparin" (werohanga subcutaneous) i roto i tona hanganga konupūmā waihā me te tote nadroparin, e kua rewa i roto i te wai injectable.

Inenga o te whakauru kaha he 2850 AU i roto i 0.3 ml; 3800 AU 0.4 ml; 5700 AU 0.6 ml, 0.8 AU 7600 ml, 9500 AU i roto i te 1 ml.

Ko te faaineineraa Ko te wai mārama ranei paku opalescent, e kua he tae kōwhai marama ranei rawa taekore.

herea Nadroparinovaya tote pūmua pai ki antithrombin III, e ai inhibition whakatere o te tauwehe Xa. Ko te taonga whakahohetia inhibitor whakarato huringa o tauwehe kikokiko, Whakahekea toto pokey me nui haere uruhanga mōtepe membrane me ngā pūtau granulocytic. Na kawea ana e ia pānga antithrombotic o te tarukino.

Werohanga "Fraksiparin" whakaritea ki te ārai i te huru thromboembolic ka mahi whawhe orthopedic o huru me te tātari toto. Kei te whakahaere te tarukino ki te tūroro he mōrearea nui o toto katinga hanganga, whakapeka iti hoki romahā me te mate ngakau, iu pectoris angina, myocardial uaua myocardial auheke ki te hapa Q-poipoi.

Ko te whakamahi o anticoagulants i roto i te whanautanga tamariki

heparins iti taimaha rāpoi i roto i te hapū e faataahia ki te tūroro e whai toto disorders ki kahore i hanga nga clots toto placental e arahi ki te materoto, ki preeklampsicheskomu o te pēhanga toto tiketike, tipitipi i te tūru tamaiti ki toto taimaha, roa te tupu o te ira i roto i te kōpū, meinga iti taimaha pēpi.

E whakaritea taua anticoagulants mō wahine i roto i te tūranga ki te mōrea taea o te katinga hanganga i roto i te uaua hohonu, hei tauira nga topito o raro, me te pukapuka uaua occlusion.

LMWH therapy Ko te tukanga mauiui, i roto i nei i te manawanui hapu tomo tarukino rā i raro i te kiri i runga i te puku.

Heoi, i whiwhi i roto i randomized haumanu i hua whakamātautau e whakamatau e te whakamahi o taua anticoagulants he maha kore hāngai ki te pānga pai. kitea hoki e heparins iti taimaha rāpoi taea therapy kino e pā ana te tinana o te whaea ki ake te toto, a ka heke te mamae te tauturu i roto i te mahi.

Kua whakaaturia enei rangahau e te whakakāhoretanga o te maimoatanga anticoagulant taea te whakaora maha wahine i tohu mamae faufaa i mau ana i te tamaiti.

Ko te tohutohu i runga i te whakamahi o teuteu e hāngai ana i runga i te iti therapy heparin taimaha rāpoi contraindicated te i roto i te hapū.