Rongoā paturopi "Remedy": tohutohu mō te whakamahi, ritenga tūturu

maimoatanga o ngā tukanga hopuhopu nāianei, e taea kahore whakamahi o raau taero antibacterial. Ko te ātete tonu te piki haere o microorganisms hanga te rapu mō taero hou te whakamahi o ngā o koroheke, paturopi kï ranei. Ehara i roto i manakohia o te whakamahi kouma o antimicrobials itehia e te whakarite o whakakeke paturopi whanui-hihinga, hei utu o te aro mātai tuatahi o te tūtohutanga o otaota ki te raau taero i roto i tenei rōpū. Drug "Remedy", nona nei pharmacokinetic nui me painga pharmacodynamic i roto i te maha o fluoroquinolones e piki whakamahia mo te maimoatanga o mate hopuhopu o etiologies rerekē.

āhuatanga Clinico-pharmacological

Ko te medicament "Remedy" ranei "levofloxacin" (International Nonproprietary Ingoa) ko he paturopi i te fluoroquinolones raupapa, te tikanga mo te ara enteral me parenteral o whakahaere.

Na roto tona ahua "Remedy" (ako ā-homai rite taua mōhiohio) he monoftorhinolonom - poinanaha o ofloxacin, a i roto i te rite ki te tahi atu raau taero, roaa painga pharmacokinetic nui:

• bioavailability waha he 100%, te tohu o te hononga ki te pūmua wē rite tiketike rite 40%;
• kitea mōrahi raau toto serum te 1-2 haora i muri i te mea rite ki taua whakahaere rō-uaua e whai ake nei whakahaere-waha;
• "Remedy" e āhuatanga e te nui haere rōrahi o tohatoha i te tinana, e tika ana ki te kătahi kaha ki te kikokiko;
• He he roa hawhe-ora o te rauropi e ai anake te horopeta kotahi o te tarukino ia ra.

Hoatu e te nui fluoroquinolones pānga haumanu ai auau tere o ara i roto i te kukū toto o te raau taero whakaora, te tawhā pharmacokinetic faahitihia whakarato tikanga pai mo te oti whakakorenga o microorganisms.

E ai ki to ratou momo o mahi i runga i te tupu me te uri o te huakita, "Remedy" kua he pānga bactericidal, pākaha i runga i nga momo kaha o te huakita pathogenic kore anake, engari ano hoki i roto i te vegetative me tautauā.

Pākia o te tahi mau raau taero puta i roto i hepatocytes i deacetylation pitihāoratanga ranei. Heoi, excreted e pā ana ki te 5% o te raau taero e te whatukuhu rite metabolites, ka tukua te toenga kei te roto i filtration glomerular me secretion tubular. Me kï reira e muri i whakahaere-waha o te wahi nui o te tarukino (e pā ana ki 70%) excreted te i te tinana i roto i te 24 haora i te mimi, ka whakakorea e pā ana ki 80% o te horopeta te i muri i 48 haora. He iti te wahi o excretion o te raau taero i roto i te wahi gastrointestinal me he anake e pā ana ki 4%.

A, no te whakamahi i te raau taero i roto i pota o runga i 1000 mg ia ra (papa rua-rā o 500 mg) i reira he iti tūponotanga ka o te whakawhanake katoahia.

tikanga o te mahi

Ko te tikanga o te mahi tarukino i runga i inhibition o paru motuhake i huaina DNA gyrase, whai wāhi nei i roto i te tukanga tukuruatanga o rauemi ira mā te korenga oa coils pai i roto i te DNA kino helix. Ka rite ki te hua o te inhibition o te tukanga paru takahia o te tāruaruatanga DNA, wehenga pūtau, puta pūtau mate.

"Remedy": tohutohu mō te whakamahi me te tohu

Ki te rā, te tohu matua mō te e tuhituhia tukanga he etiology kitakita hopuhopu, meinga e taumahatanga i haria o microorganisms ki te rongoā paturopi i roto i te tūroro pakeke atu i te 18 tau.

Te faaineineraa "Remedy" ara pai mohiotia i roto i te maimoatanga o romahā mate kitakita o nga mate wahi romahā o runga me raro pērā i Bronchitis whakapeka, pakohu kakā, mate inflammatory o te kiko pūkahukahu. Ko tenei tika, ki runga ake katoa, he kătahi tarukino pai ki te epithelium o nga bronchi me pūkahukahu te wahi noa i muri hanga te whakahaere tarukino tuatahi kukū whai hua.

pai te taua waihanga whakamahia ki te hamani mate mimi wahi (pyelonephritis, cystitis, urethritis, me ētahi atu), Biliary mate wahi, prostatitis, mate kiri, mate intraabdominal me sepsis.

I roto i te tikanga ki te hamani mate hopuhopu o nga Airways whakaritea "Remedy" te (i runga i te pakeke mate rānei) 1-2 wa he ra ki 500 mg ia papa, te faaineineraa injectable ranei.

Hoki te maimoatanga o te mate mimi he rawaka horopeta o te faaineineraa 1, 250 mg kotahi te ra, a i roto i ngā take kino, ka taea e te horopeta ia kia 500 mg ( "rongoa 500"). ka mea tohutohu mō te whakamahi taea te whakakapi horopeta rua-rā o 250 mg i te 500 mg kotahi i runga i te pakeke mate rānei.

Hoki te maimoatanga o ngā mate hopuhopu o te kiri, me te mucous "Remedy" whakaritea i roto i te inenga o te 250 mg rua he ra.

contraindications

contraindication Absolute ki te fariiraa i tarukino he hypersensitivity, me tauhohe mate pāwera i roto i te aroaro o te hītori o ngā rongoā fluoroquinolones.

raraunga papû-e pā ana i te whakahaere o te raau taero i roto i hapūtanga, e kore, rite ki te rangahau te mana o te pānga teratogenic embryotoxic ranei kua kore i whakahaere.

I roto i te tirohanga o tenei whakarite "Remedy" mō wahine hapu kia karohia, anake i roto i te wā i reira ko raro atu i nga painga i reira te tūpono o whakahaere o te taonga.

I roto i te take o te tarukino i roto i ngā tūroro mate ana i porphyria, kia meinga keia o te mate.

Ki te kia tono tūpato otinga e whaowhia motuhake ki tūroro ki pāpaka mua o te pūnaha io pokapū (patu, patua ngakau, ngaukino whara roro), e tika ana ki te tūponotanga nui o āhua takiri.

Hoki tūroro e mahi ki te tikanga matatini i te mahi peia he waka ranei, kahore he tohutohu motuhake, engari whakaaro ki te taea o ngā pānga taha i roto i te pūnaha io pokapū i roto i te puka o te sleepiness, whakama, me etahi atu. Hoki kia pehi tenei take i tenei ahua o te mahi.

pānga taha

Ko tētahi o nga pānga taha tino nui e whakawhanake i roto i ngā tūroro te whiwhi fluoroquinolones, ko te mate o te wheua ngohe kino e tika chondrocytes epiphyseal me te kiko ano. I roto i te tirohanga o tenei tarukino contraindicated te i roto i nga tangata i raro i te 18 tau o te tau, me te wahine e hapu ana. Me kï reira e i roto i tūroro kitea i runga i te 18 tau o te tau ki te puipuitua o te whakamahi wā roa-o te tarukino i takanga o arthralgia pōrearea o hononga ranei. I roto i te tahi atu pānga taha ko te whai.

I runga i te wahi o te wahi gastrointestinal - whakapairuaki, ruaki, mate o hiahia, te ahua o sensations fiemālie i roto i te rohe epigastric, kia wheako koutou toto gastrointestinal me te whanaketanga o te köpiro; ake i roto i transaminases i roto i te wē toto.

I runga i te wahi o te pūnaha pokapū io - te whanaketanga o tohu encephalopathy, ānini, whanoke, mate o mahara, disorders moe, me ngā rerekētanga auau i roto i te tūāhua, te ahua o paresthesias, moemoea me horihori.

I runga i te wahi o te pūnaha ārai mate - te whanaketanga o ngā tauhohe mate pāwera pērā i ponana kiri, minamina, a taea whakawhanake photodermatitis whakaratohia insolation tiketike.

Mai i te pūnaha mimi - te whanaketanga o te crystalluria.

Ko te pūnaha takanga romahā pea o bronchospasm me i te pūnaha circulatory - te heke koi i roto i te pēhanga toto, e suka whanaketanga tauhohenga i te hemostasis pūtau (i roto i te puka o te thrombocytopenia, me ētahi atu).

Ngā pāhekoheko ki ētahi atu taero

e kore e drugs fluoroquinolone whakahaere tahi me patu waikawa, rite tino whakaiti tenei te absorption me bioavailability o paturopi. Ehara i tukutahi tono "Remedy" tūtohutia ki teuteu rino, me te raau taero e pā te mahi mahi o te pūnaha io pokapū. I tua atu, i reira he taunakitanga e pā ana ki te pānga o te probenecid me te cimetidine runga i te excretion o te tarukino (e taea ki te whakaiti i whakakorenga o paturopi enei matū).

tohu unambiguous o taunekeneke tarukino ki kore levofloxacin. I roto i te tirohanga o te pākia e iti o te raau taero i roto i te kiko ate, me te kore o te ngā ki whākōkī o te rōpū o te cytochrome P450 «Remedy" e kore e huri i te mahi whakamutunga, engari ahakoa tenei, kia rite ki te tahi atu i te mau melo o te fluoroquinolone, kia kore e ngā te tarukino me taero teofilinovogo raupapa me te autaki anticoagulants, e tika ana ki te hua ka taea i roto i to ratou kukū i roto i te toto.

Ko te whakamahi o te raau taero i roto i te whāngai ū

Ki te rā i reira he kore ngā mōhiohio e pā ana ki te kaha o te tarukino ki tomo te waiu uma o te whaea. Ki te reira te mea he mea hei akiaki ia o therapy paturopi i roto i te uma-kai, te mutu whakamutunga mo te wa tūtohutia (tei te roanga i runga i te pakeke o te mate, me te roanga tūmanakohia o maimoatanga rongoā paturopi). Ki te tika i roto i te tikanga ki te mau tonu te hohipera hua köurarangi wā ranei mutu hohipera katoa i roto i te tikanga hauora.

I roto i te wā tino, kia uma-kai me paturopi i roto i te aromatawai mōrearea mo te tamaiti, me te whaea.

puka Tuku me te inenga

hua "Remedy" Kei roto i rua puka: hoki whakahaere enteral me parenteral. Hoki whakahaere-waha reira puka papa kei roto 250 500 ranei mg o te tarukino (aua i raro i te ingoa o "Remedy 250" me "500 Remedy" hokohoko). Hoki whakahaere parenteral otinga e whaowhia wātea.

E riro "Remedy" Papa 1-2 wa he ra i te aroaro o te kai kore, ko te wai i roto i waenganui i ona tikanga, ka romia ki te wai rawaka ranei. I roto i te kaupapa o te hiahia ki te wehe i te horopeta i te hawhe o te raau taero, e taea te papa pakaru i runga i te tapanga kia rua nga wahi.

Hoki whakahaere parenteral, he wātea ki nohanga whakauru kaha o 500 mg / 100 ml o otinga otinga mō te werohanga ( "rongoa 500"). I roto i te take o te werohia rō-uaua, ko kore tere atu hoki te 1 haora te whakataki o te tarukino.

tūtohu atu whakawhiti ki te puka papa e i muri i whakahaere whaowhia. Tei roanga tūmanakohia i runga i te pakeke o te mate, me te tūtohutanga o microorganisms pathogenic ki te rongoā paturopi. E ākina therapy (ahakoa o te puka o te whakahaere) ki te haere tonu mō te 3-4 ra i muri i māori o te pāmahana tinana. e kore te maimoatanga motuhake, me te whakamutunga wawe o te raau taero tūtohutia hoki o te mōrea tiketike o tauhohe taha me te whanaketanga taea o ātete ki te microflora tarukino.

Ara

I mua obliges therapy te whakamahi i "Remedy" ā-ako e pupuri ana tauira mō te tūtohutanga manga koiora ki te tarukino. Heoi, mai i te whānui o te mahi, kia tīmataria maimoatanga i waho whakahaere i te tauira, aru i te faaotiraa o te tarukino whai hua tino.

Vahe he rongoa "Remedy", kia kia utua tokanga makehe ki te tātari hāngai ki te arotake i rere toto tākihi, mai excreted te nuinga o te raau taero e na roto i te whatukuhu reira. A, no te ki te kia whakaritea maumaui o te tarukino me te mahi horopeta whakamutunga i roto i runga i te whakawātea o te creatinine endogenous.

Kei te tino puka faaineineraa whaowhia rāhuitia i konatunatua ki te rongoā mō te werohanga, e whai he tauhohenga kawakore (te konutai), me ki heparin. Hoki te whakaaro o dilutions whaowhia rasvor "Remedy" hototahi ki isotonic otinga konutai pūhaumāota, isotonic kūhuka otinga "Ringers".

I roto i te fariiraa, "Remedy" kia karo i inu waipiro, e whakarei ake te reira i te pānga paitini o levofloxacin i runga i te pūnaha io pokapū me te faaiteraa atu korerotia o pānga taha.

Ki te, Heoi, faaoti i runga i to ratou ake ki te tono i te "Remedy", tohutohu mo te whakamahi, analogues, kia kia uia āta, no te mea ko reira te tini o te mōhiohio me te faarava'iraa i tika mōhiotanga o te faaineineraa e te karo blunders.

Storage me supply o pharmacies

tikanga rokiroki Motuhake kore te te tarukino hiahiatia. whakarite tōna haumaru te i ambient pāmahana ki te 25 degrees. Mai i te "Remedy" pharmacies (paturopi) whakahaunga.

A, no te hoko i te hua ko te tino tika ana ki te whakarongo ki te tapatahi, me te haumaru o te tākainga, rā production me te ora papa. Me tika kia hakari i roto i te pouaka o te rongoā "Remedy" ā-ako. Me kia Papa i roto i-te kounga tiketike tākai. Ka taea e te tirotiro e koe te mohio tūturu o reira (rite kia mea he ke). Ko e tika ana ki te meka e ake me te ake maha i roto i te mākete ho'oraa i reira he loi me fakes, e i pai kore e taea e ki te whakarato i te pānga antibacterial tika ka tangohia-waha, me i kino rawa tenei - meinga pānga taha nui. Na reira, whiwhi i te tarukino, e kore e e mangere ki te ui i te rongoā e pā ana ki te aroaro o te tiwhikete kounga, te whakau i te takenga o te tarukino, "Remedy" (papa). Me whai tohutohu mō te whakamahi (tarukino whakahaunga hokona) mōhiohio e pā ana ki te takenga mai o nga moni.

tuwhena rawa

I roto i te take kahore he tuwhena rawa raau motuhake. Tohutanga i te taikaha o te horopeta he tika te nuinga ki te mana o te muri i runga i te mahi mahi o te pūnaha io pokapū. I roto i tenei take i reira he whakama hinengaro, te momoe, whanoke, me tohu o te excitation o te pūnaha io i roto i te puka o te āhotea, haurangi, me etahi atu.

hāngai Treatment te i te excretion arä o te tarukino. Homai te bioavailability tiketike, me te tohatoha o te raau taero, puta noa i te tinana, e whai hua ana tikanga tātari toto detoxification. He mea tika ki te aukati i te rere o te raau taero i roto i te tinana, me te ki te kawe i te maimoatanga symptomatic.

No te mea o te whakakorenga nui o "Remedy" i filtration i roto i te tākihi glomeruli tikanga whai hua o te detoxifying reira ko ki te whakamahi i rongoā tote waiwai, me te e whaowhia o taero diuretic momo koropiko mahi.

Reviews o te faaineineraa

Fele kitea whakautu pai i runga i te tarukino hoki o tona kakama tiketike mo te maimoatanga o mate hopuhopu o ngā etiology. Ka rite ki kī i roto i te "Remedy" tohutohu mo te whakamahi o te arotake tarukino kua mahue tūroro kore anake, engari ano hoki rata, e tuhia tona pai tiketike, ki runga ki te maimoatanga o te mate nosocomial me nosocomial.

arotake tōraro me te inoino tarukino mahue i roto i nga tūroro matua. Ko e tika ana ki te whanaketanga o ratou pānga taha ranei hē o "Remedy" tenei. Ako, Heoi, homai he mōhiohio rawa whānui mō tenei hua. E tika ana ki te whakamahi o te raau taero i roto i te wā i reira ko reira hua e tika ana ki te hanganga ture-kore o te hihinga o mahi antibacterial o te mate koiora arotake tōraro. Me kï reira e maha waiho nga whakaaro nui tūroro ki whaiaro medicate-a tango i te whaiaro-i whakaritea, i runga i te kupu tohutohu o hoa "Remedy" hoa ranei (ako i te wa ano e maha arongia, e kore e tino tūtohutia) ranei. urupare tōraro i ngaio hauora e kore e whakaritea e kitea. Ko tenei e tika ana ki te whakamahi tika, me te kouma o ngā rongoā (mōhiohio e pā ana ki te "rongoa 500" Kei ā-rawaka ngā mōhiohio mō te whakamahi tika o te tarukino).

analogues Drug "Remedy"

Hoki te faaineineraa "Remedy" analogs ako whakaahuatia e whai ake: mai te tarukino ko te levofloxacin paturopi fluoroquinolone, e taea te whakaaro analogues tiketike-kōeke tata taero katoa o rite hanganga. Me kï reira te tuatahi o te katoa "Levofloxacin", "Sol", "wani", "Levoksimed" I roto i enei, a he maha ētahi atu. Hoki "Remedy" (papa) tono Kaiwhakamahi whakarato analogs o taero pērā i "Leflok", "Floksium" me etahi atu.

mutunga

Ko te kaha wāhanga "Remedy" tarukino - he levofloxacin paturopi. Ko ia he kaihoko antibacterial pai ki te whanui-hihinga pānga bactericidal. Nā ki te pā iti o ngā pānga taha me te kore o te ātete ki te rongoā paturopi rerekē taumahatanga kitakita, kua pai tono i roto i te haumanu mahi "Remedy". Tohutohu mō te whakamahi homai mōhiohio rawa whānui e pā ana ki te mahi o te tarukino.