Whakaahuatanga Hua "Vikeyra Pak". Reviews peratia, rawa te whakamahi o Viekira Pak

tukinotia faaineineraa o te whakatupuranga hou o te kakā C "Vikeyra Park" arotake i roto i te pai tino. Ko te tika tenei matua ki te tōtika tiketike o te tarukino.

Ko te mahi o te tarukino "Vikeyra Pak"

hāngai ana te mahi o te tarukino i runga i toru ngā momo o raau taero patu huaketo. Tenei "dasabuvir", "Ombitasvir" me ritonavir-putanga "Paritaprevir". Ka rite ki raau ao-mohiotia i huaina "Harvoni", "Vikeyra Pak" maimoatanga tino whai hua - te wā i 97 ki te 99%. Ko te tarukino hoki kakā ko te tuawha whakaaetia i roto i te United States. I mua ia, pai kua whakamātautau haumanu haere te "Olizio" (te ingoa i roto i Russian - "Sovriad"), te ngā "Harvoni" me "Sovaldi".

ngā mōhiohio whānui e pā ana te whakatupuranga hou o te faaineineraa hauora

"Vikeyra Pak" (urupare peratia i mua i te mea he tokomaha rawa, no te mea rēhita i te tarukino i roto i Russia anake i roto i te Mei 2015) tukuna e te kaiwhakanao Airihi me tākai i roto i te United States. hokona te raau e mana i roto i Russia, ka taea e te tono koe i te reira i tetahi rongoā. whakauru Active o te medicament:

• ritonavir;
• dasabuvir;
• paritaprevir;
• ombitasvir.

E pā ana te reira ki raau taero patu huaketo mahi hāngai (J05A). Tenei medicament - he tarukino utu. Hei tauira, maimoatanga mō te 12 wiki e utu 950 mano moni - tenei tikanga he maha o pōkai "Vikeyra Pak" (te utu i roto i te St Petersburg). arotake Kiritaki ngā mōhiohio e, i roto i rite ki te mohiotia "Harvoni", te utu o nei i roto i Europe he e pā ana ki 60 mano tara, te tarukino Irish ano tino wātea ana mō te hoko. Ko te kōwhiringa pūtea tino i roto i te katoa ko te tarukino rite i huaina "Sunvepra" (utu - 400 mano moni mo te maimoatanga o te roanga kotahi).

Ngā me tikanga o te rokiroki

Ka taea te pānui i te whakaahuatanga ki tonu o te faaineineraa "Vikeyra Pack" i runga i te mōkihi o rongoā. Kia mau kia waiho te reira i roto i te wahi uaua ki ngā tamariki i te pāmahana o te kore neke atu i te 25 degrees. Kaua e tango i te raau taero i muri i te paunga o te wā mana - 2 tau. ngā mōhiohio katoa e pā ana ki te whare "Vikeyra Pak": utu, tohutohu mo te whakamahi, iwi tūturu pangia therapy ki enei taero whakarāpopototia i roto i tenei tuhinga.

Ko te whakamahi o "Vikeyra Pak" me ngā pānga taha

Whakaae o te tarukino i raro i te arotake mō te maimoatanga o te kakā C ko ki te kia kawea i roto i te wā i te kai, me te pūngoi ngako ranei ihirangi o te hua e kore e mea faufaa. I roto i te ata kia tango kia rua papa paritaprevira / ritonavir / ombitasvira, me kotahi te pire dasabuvir. kia te whakamutunga kia pau me i te ahiahi. Ētahi tūroro i te tākuta whakarite ai te tikanga o "Pack Vikeyra" i roto i te taha ki "Ribavirin". Ki te mea kua tīpakohia e koe tika te therapy taua, "Vikeyra Pak" e manakohia i te nui o ono pire te ra:

• i roto i te ata, i te ra - kotahi pouri me te rua papa marama;
• i roto i te ahiahi - kotahi pouri;
• rua ia ra "ribavirin" i roto i te inenga o te 500 mg.

Ko te whakamahi o "Vikeyra Pak" (arotake ngā kōrero me ngaio ite) kia tika whakaae ki te tākuta. Ki te te te mamae i te manawanui i tahi-mate ki HIV, ko te talena inenga te taua, me, tika - i roto i ngā kai. I runga i te tākai kore e whakarārangitia pānga taha nui i tango i te raau taero. Ko te ine taea tino noa, kia rite ki arotake me tohutohu - ko tenei:

• asthenia;
• tihore tauhohe, tae atu pruritus;
• rohirohi;
• kore o te moe;
• whakapairuaki.

Ko te kaupapa o te akoranga o te maimoatanga

"Vikeyra Pak" kaupapa maimoatanga ngā te huinga o toru taero, whakawhanakehia e te kamupene "EbbVay" me te momo pharmacokinetic enhancer i huaina "Ritonavir" mo te tarukino. whakaritea talena tarukino mō te rongoā kakā C te mo te maimoatanga o te HCV (tohuira 1a) i roto i ngā ki "Ribavirin". Me te akoranga i te iti rawa i te tonu 12 wiki. Hoki tohuira tukinotia rite 1b, engari kahore te whakaurunga o te tarukino muri. I tua atu, "Pack Vikeyra" (tukinotia urupare i raro i te kaupapa titiro neke atu i faahiahia) tikanga hoki maimoatanga o te tūroro ki te cirrhosis utua. Course - 24 wiki ki "Ribavirin" mo te tohuira 1a, i roto i te tahi atu te wā - 12 wiki.

tutuki Paturuhia whakautu virological i roto i tūroro (tohuira 1a) ki ngaro o te cirrhosis i roto i 97% o ngā take, i 1b - 100% tohua e i tū te therapy huinga momo. cirrhosis ate utua tae SVR te taumata o 95% (roa Therapy 24 wiki) mo te 1a tohuira, i roto i te tahi atu te wā (1b) tohu tata kotahi rau ōrau.

contraindications

Te faaineineraa "Vikeyra Pak" (whakawākanga tukinotia fakamau reira) kua, rite ki tetahi tarukino, he maha o contraindications. Ko ētahi o ēnei te whai ake:

• mahi ate decompensated;
• hypersensitivity ki ritonavir;
• hemoglobinopathies;
• wā kotahi whaia "ddI" therapy;
• hapūtanga;
• te fariiraa i inhibitors mahi kaha;
• te fariiraa i whāpoapoa kaha.

Me kï reira e te whakamahi o tenei rongoā mō ngā tamariki e kore i nei i tae te tau o te nuinga, kei te tino rāhuitia. I tua atu, lactating maimoatanga wahine kore e tūtohu e tika ana ki te kore o te mōhiohio tika e pā ana ki te kătahi o matū kaha "Vikeyra Pak" i roto i te waiu, uma tangata. Kia tino hiahia ana koe ki te mutu whāngai ū.

Tūpato i roto i te tono

korerotia te Tari US o Kounga Mana o ngā rongoā e taea "Vikeyra Pak" me analogues, e kua whakamahia ki te hamani kakā C arahi ki kino ate tina heke. Ko rawa pono o te iwi ki te hauātanga i roto i te mahi o te okana faufaa tenei. Hoki tenei take, i hanga te kaihanga kua etahi menemana ki nga tohutohu mo te whakamahi o te raau taero.

Ki te he pānui manawanui e puta te wahi o te therapy pinepine te ngenge me te rohirohi, āmai, maha mate me te ruaki puta, ka tīmata ki te tahuri kiri kōwhai, ka me waiho e koe mohio ki te whakapā atu te tangata mo te awhina no o te meka i reira ko te tupono o kino ate. Kāti te tango i tēnei rongoā kahore whakaaetanga o to koutou tākuta i roto i tetahi take e kore e taea, ka rite ki tenei e taea meinga ātete o te tinana ki ētahi atu raau taero, whawhai kakā. Ko te tākuta i te hōhipera kia waiho te wa ki te mau i te manawanui ki te whakakore i te tohu o te ate mahi. Ko ētahi o ēnei:

• toto i varices esophageal;
• ascites;
• ake i roto i te taumata bilirubin;
• encephalopathy.

Pērā medicaments rite "Vikeyra Pak" whai wāhi ki te whakaiti nui i roto i te nui o te kakā C huaketo i roto i te tinana tangata, i roto i te tua, kia pōturi te ahunga whakamua o te mate.

Prescription o te tarukino hou mō te kakā C

Āhuatanga Viekira Pak maimoatanga ngā te huinga o pota maha o etahi raau taero e kua whakamahia i roto i ngā ki "Ribavirin" e kore ranei. I whakaaetia te tarukino mo te maimoatanga o tūroro mate i ate cirrhosis me C. kakā I mua i te tīmata koe te whakamahi i te raau taero i roto i te pātai, he mea e tika ana ki te whakamōhio i te tākuta e pā ana ki te whai ake:

• te aroaro o HIV mate;
• atu mate ate, i roto i te tua ki te kakā C;
• te whakamahi o te whakawhānau, tae atu ethinyl estradiol.

He mea utu te tuhituhi e i roto i nuinga o te wā e te kaikā i te pānga taha o te tarukino me te ritenga o te kiri, te kore o te moe, me te inanga, ki ruakina. E ai ki te tiaki 2015 hauora ngaio whakahau rongoā i huaina "Pack Vikeyra" mo neke atu i te 11 000 te iwi.

He aha te katoa kia mohio kei te pangia te manawanui maimoatanga?

Ki te whakamamaetia te manawanui he akoranga o te maimoatanga 12 ranei 24-ra, e kore e taea ki te mutu i waho te whakaae o te tākuta ki a ia. Tenei e taea e arahi ki te putanga o te ātete ki ētahi atu taero hoa. Ko reira utu te haamana'oraa e te mea e whakatu te manawanui atamira o te mate ate, te "Pack Vikeyra" Ka taea e meinga kino okana nui, tae atu kore ate. Kia tino ki te rapu awhina i te hōhipera, ki te kite hohokitanga auau o ngā tohu pēnei i te ruaki, kōwhaitanga o te teatea, ohorere mate tākaha o te hiahia, kumete marama-tae.

I mua i te tīmata maimoatanga, e tūtohu ana ki te pānui i te tohutohu. kia kōrero Tetahi pātai ki tō tākuta. E kore e taea e koe te huna i tetahi mōhiohio e pā ana ki te āhua o te hauora, tae atu ki te puta ngā pānga taha o āpiha 'Vikeyra Pak ".

Aromatawai o te haumaru

faaineineraa Haumaru "Vikeyra Pack" arotakea i runga i te kaupapa o ngā raraunga o te tuarua, me te tuatoru wā tamataraa haumanu tata 3,000 tūroro pangia maimoatanga i roto i ngā ki "Ribavirin" me waho. A, te whakamahi i ngā raraunga i roto i ngā tūroro mate ana i ate cirrhosis. tauhohe kino i whakamahi i kitea i roto i te 20% o te wā. Ko te tohu tino noa - he whakapairuaki, me te rohirohi kino. Mutu maimoatanga no o ngā pānga taha noa 1.15%. anō ratou ratou akoranga i muri i arumanga o te therapy - 1.4%. No te mea o te tauhohe kino o te rauropi ki te inenga tarukino i iti, "Ribavirin" 8% o tūroro.

i kitea Rerekētanga i te whakautu o te rauropi ki te tarukino i roto i tūroro ki a kahore ate cirrhosis. I roto i te ako haumanu wāhi matou tūroro nei ka mau "Vikeyra Pak" me kahore "ribavirin". tohua te reira i te tauhohenga anake ki te raau taero, i roto i tenei take - te putanga o te patito i runga i te kiri. maimoatanga faahope mō tenei take 0.4 anake%, hanga e he whati i roto i te therapy kua pā ana ki 0.6% o tūroro. I tū te aromatawai haumaru o te tarukino "Vikeyra Park" i runga i te maha o ngā tawhā (ki a kahore cirrhosis, ki te tua o "Ribavirin" kore te akoranga), me te i roto i te akoranga o te therapy, arā, 12 wiki, me te 24.

utu tata "Vikeyra Pak" i roto i Russia, a ki waho

I roto i te Hau Amui no Marite o Amerika "Vikeyra Pack" utu e pā ana ki 84.000 tara (tae atu ki ngā ra 12 o te maimoatanga), te kaupapa here utu i roto i te Russian Federation, pera i roto i te maha atu whenua Pākehā, he tino rerekē.

I paetukutuku ngā i runga i te Ipurangi e taea e kite koe i nga utu rerekē o te rongoā Irish. Hoki ngā pūtahi hauora i roto i Russia utu "māngai Vikeyra Pak 'ko e pā ana ki 300 mano moni mo te kotahi marama o te maimoatanga. I roto i te akoranga 12-wiki ka whai ki te utu e pā ana ki 850-900 moni. Ko te kupu, te hunga e whakaritea ana ki te maimoatanga i 24 wiki, Me ki te hoko rongoa mo te kakā C te kore iti iho i te 1.5 miriona moni.